Molecular structure of Brusatol, CAS Number: 14907-98-3
Brusatol (CAS 14907-98-3)
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Alternate Names:
13,20-epoxy-3,11β,12α-trihydroxy-15β-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-picras-3-en-21-oic acid, methyl ester
CAS Number:
14907-98-3
Molecular Weight:
520.5
Molecular Formula:
C26H32O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Brusatol (CAS 14907-98-3) References
- Brusatol attenuated proliferation and invasion induced by KRAS in differentiated thyroid cancer through inhibiting Nrf2. | Gong, Z., et al. 2024. J Endocrinol Invest. 47: 1271-1280. PMID: 38062319
- Sulforaphane Regulates Macrophage M1/M2 Polarization to Attenuate Macrophage-induced Caco-2 Cell Injury in an Inflammatory Environment. | Yi, T., et al. 2024. Iran J Immunol. 21: 37-52. PMID: 38314669
- Brusatol's anticancer activity and its molecular mechanism: a research update. | Xi, W., et al. 2024. J Pharm Pharmacol. 76: 753-762. PMID: 38394388
- Arenobufagin inhibits lung metastasis of colorectal cancer by targeting c-MYC/Nrf2 axis. | Wang, M., et al. 2024. Phytomedicine. 127: 155391. PMID: 38452690
- KLF4 suppresses anticancer effects of brusatol via transcriptional upregulating NCK2 expression in melanoma. | Li, X., et al. 2024. Biochem Pharmacol. 223: 116197. PMID: 38583810
- Vanillylacetone attenuates cadmium chloride-induced hippocampal damage and memory loss through up-regulation of nuclear factor erythroid 2-related factor 2 gene and protein expression. | Al-Hashem, FH., et al. 2024. Neural Regen Res. 19: 2750-2759. PMID: 38595292
- Brusatol hinders the progression of bladder cancer by Chac1/Nrf2/SLC7A11 pathway. | Yu, X., et al. 2024. Exp Cell Res. 438: 114053. PMID: 38663476
- The Experimental and In Silico-Based Evaluation of NRF2 Modulators, Sulforaphane and Brusatol, on the Transcriptome of Immortalized Bovine Mammary Alveolar Cells. | Ford, HR. and Bionaz, M. 2024. Int J Mol Sci. 25: PMID: 38673850
- Exposure to polystyrene nanoplastics induces hepatotoxicity involving NRF2-NLRP3 signaling pathway in mice. | Wen, Y., et al. 2024. Ecotoxicol Environ Saf. 278: 116439. PMID: 38728945
- The Nrf2/HO-1 pathway participates in the antiapoptotic and anti-inflammatory effects of platelet-rich plasma in the treatment of osteoarthritis. | Du, G., et al. 2024. Immun Inflamm Dis. 12: e1169. PMID: 38860757
- Brusatol induces ferroptosis to inhibit hepatocellular carcinoma progression by targeting ATF3. | Wan, Y., et al. 2024. Chem Biol Drug Des. 103: e14565. PMID: 38862254
- Brusatol alleviates pancreatic carcinogenesis via targeting NLRP3 in transgenic Krastm4Tyj Trp53tm1Brn Tg (Pdx1-cre/Esr1*) #Dam mice. | Zhang, J., et al. 2024. Biomed Pharmacother. 177: 116977. PMID: 38901203
- Brusatol improves the efficacy of an anti-mouse-PD-1 antibody via inhibiting programmed cell death 1 ligand 1 expression in a murine head and neck squamous cell carcinoma model. | Wu, Y., et al. 2024. Arch Oral Biol. 166: 106043. PMID: 38968906
Inhibitor of:
14-3-3 σ, AFX1, BACH1, DHTKD1, FOXR1, glutathione S-transferase mu (GSTM), KIAA0776, MGST1, NF-E2 p18, NRF-1, SKN-1, and TARSL2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Brusatol, 5 mg | sc-507427 | 5 mg | $145.00 |