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Brompheniramine Maleate is a histamine H1 receptors antagonist. Brompheniramine Maleate also functions as a moderately effective anticholinergic agent, and is likely an antimuscarinic agent similar to other common antihistamines such as diphenhydramine. Brompheniramine Maleate is an antihistamine drug of the propylamine (alkylamine) class. Brompheniramine Maleate has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. Brompheniramine Maleate also has analgesic-sparing (potentiating) effects on opioid analgesics, commonly reducing codeine, dihydrocodeine, and hydrocodone requirements by 10 to 35 percent. Brompheniramine Maleate is metabolised by cytochrome P450s.
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