Brompheniramine Maleate CAS: 980-71-2
MF: C16H19BrN2•C4H4O4
MW: 435.31
A histamine H1 receptors antagonist.

Brompheniramine Maleate (CAS 980-71-2)

Brompheniramine Maleate | CAS 980-71-2 is rated 5.0 out of 5 by 1.
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Synonym: γ-(4-Bromophenyl)-N,N-dimethyl-2-pyridinepropanamine Maleate; 2-[p-Bromo-α-[2-(dimethylamino)ethyl]benzyl]pyridine Maleate; (±)-Brompheniramine Maleate; Bromphen Maleate; Dimegan; Dimetane; Parabromdylamine Maleate; Parabromodylamine Maleate; Veltane; dl-Brompheniramine Maleate
Application: A histamine H1 receptors antagonist
CAS Number: 980-71-2
Purity: ≥98%
Molecular Weight: 435.31
Molecular Formula: C16H19BrN2•C4H4O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Brompheniramine Maleate is a histamine H1 receptors antagonist. Brompheniramine Maleate also functions as a moderately effective anticholinergic agent, and is likely an antimuscarinic agent similar to other common antihistamines such as diphenhydramine. Brompheniramine Maleate is an antihistamine drug of the propylamine (alkylamine) class. Brompheniramine Maleate has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. Brompheniramine Maleate also has analgesic-sparing (potentiating) effects on opioid analgesics, commonly reducing codeine, dihydrocodeine, and hydrocodone requirements by 10 to 35 percent. Brompheniramine Maleate is metabolised by cytochrome P450s.


References

Walle, T., et al.: Biochem. Pharmacol., 37, 115 (1988), , Yang, W; J Pharm Pharmacol 2004, 56, 703,,,, Xu, H; Anal Sci 2004, 20, 1409,

Appearance :
Crystalline powder
Physical State :
Solid
Storage :
Store at room temperature
Melting Point :
136° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5281067
SMILES :
CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2.C(=C\\C(=O)O)\\C(=O)O

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Certificate of Analysis

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Brompheniramine Maleate  Product Citations

See how others have used Brompheniramine Maleate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 22959845  Sueyoshi, K. et al. 2012. J Chromatogr A. 1269: 366-71.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Gupta Gupta, VD. et al. (PubMed 23696050) studied the chemical stability of Brompheniramine Maleate in an oral liquid dosage form by using a stability-indicating high-performance liquid chromatographic assay method. The formulation was stable for at least 202 days when stored in amber-colored glass bottles at room temperature. -SCBT Publication Review
Date published: 2015-01-06
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