Molecular structure of Brompheniramine, CAS Number: 86-22-6
Brompheniramine (CAS 86-22-6)
Application:
Brompheniramine is a reuptake inhibitor of seratonin
CAS Number:
86-22-6
Molecular Weight:
319.24
Molecular Formula:
C16H19BrN2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Brompheniramine is a chemical compound that is used to study its effects on histamine receptors. In molecular biology, brompheniramine serves as a ligand to probe the function of histamine H1 receptors and to identify the signaling pathways they regulate. It is in binding assays to characterize the receptor′s affinity and in functional assays to assess downstream biological effects. Brompheniramine is also in studies looking at histamine′s role in immune response, where it acts to understand the modulation of immune cell activity. Studies involving brompheniramine contributes to the knowledge regarding the regulation of neurotransmitter systems and their impact on various biological processes.
Brompheniramine (CAS 86-22-6) References
- Affinities of brompheniramine, chlorpheniramine, and terfenadine at the five human muscarinic cholinergic receptor subtypes. | Yasuda, SU. and Yasuda, RP. 1999. Pharmacotherapy. 19: 447-51. PMID: 10212017
- Electrophysiological effects of brompheniramine on cardiac ion channels and action potential. | Shin, WH., et al. 2006. Pharmacol Res. 54: 414-20. PMID: 17010640
- Extra- and intracellular formation of reactive oxygen species by human neutrophils in the presence of pheniramine, chlorpheniramine and brompheniramine. | Jancinová, V., et al. 2006. Neuro Endocrinol Lett. 27 Suppl 2: 141-3. PMID: 17159800
- Blockade of HERG K+ channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656. | Park, SJ., et al. 2008. J Appl Toxicol. 28: 104-11. PMID: 17516459
- Halogenation effects of pheniramines on the complexation with beta-cyclodextrin. | Wang, LF. 2009. J Pharm Biomed Anal. 50: 392-6. PMID: 19540697
- Pregnancy after brompheniramine treatment of a diabetic with incomplete emission failure. | Schill, WB. 1990. Arch Androl. 25: 101-4. PMID: 2389987
- Contact allergens in oral antihistamines. | McEnery-Stonelake, M. and Silvestri, DL. 2014. Dermatitis. 25: 83-8. PMID: 24603514
- Chiral separation of brompheniramine enantiomers by recycling high-speed countercurrent chromatography using carboxymethyl-β-cyclodextrin as a chiral selector. | Zhang, P., et al. 2016. J Sep Sci. 39: 2300-6. PMID: 27080368
- Brompheniramine as a novel probe for indirect UV detection and its application for the capillary electrophoresis of adamantane drugs. | Prapatpong, P., et al. 2017. J Sep Sci. 40: 1184-1192. PMID: 28087893
- In situ immobilization of sulfated-β-cyclodextrin as stationary phase for capillary electrochromatography enantioseparation. | Zhou, L., et al. 2019. Talanta. 200: 1-8. PMID: 31036161
- Subcutaneous brompheniramine for cutaneous analgesia in rats. | Chiu, CC., et al. 2019. Eur J Pharmacol. 860: 172544. PMID: 31319069
- Determination of brompheniramine in blood and urine by gas-liquid chromatography. | Bruce, RB., et al. 1968. Anal Chem. 40: 1246-50. PMID: 4393465
- Tertiary amines related to brompheniramine: preferred conformations for N-oxygenation by the hog liver flavin-containing monooxygenase. | Cashman, JR., et al. 1993. Pharm Res. 10: 1097-105. PMID: 8415393
- Fungal transformations of antihistamines: metabolism of brompheniramine, chlorpheniramine, and pheniramine to N-oxide and N-demethylated metabolites by the fungus Cunninghamella elegans. | Hansen, EB., et al. 1995. Xenobiotica. 25: 1081-92. PMID: 8578764
- Anticholinergic properties of brompheniramine, chlorpheniramine, and atropine in human nasal mucosa in vitro. | Fang, SY., et al. 1998. Am J Rhinol. 12: 131-3. PMID: 9578932
Inhibitor of:
HDC, and Serotonin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Brompheniramine, 10 mg | sc-205609 | 10 mg | $232.00 | |||
Brompheniramine, 25 mg | sc-205609A | 25 mg | $375.00 |