Date published: 2025-12-28

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Bromotriethylsilane (CAS 1112-48-7)

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Alternate Names:
Triethylbromosilane
CAS Number:
1112-48-7
Molecular Weight:
195.17
Molecular Formula:
C6H15BrSi
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bromotriethylsilane is primarily used in organic synthesis as a reagent for introducing triethylsilyl groups into molecular structures. This compound is particularly valuable for its role in silylation reactions, where it enhances the stability of sensitive functional groups during synthetic procedures. Research involving Bromotriethylsilane often focuses on its application in protecting groups and its utility in the modification of alcohols, amines, and other reactive moieties. Additionally, Bromotriethylsilane is explored for its effectiveness in promoting cleavage reactions, which are essential for the deprotection and subsequent functionalization of organic molecules.


Bromotriethylsilane (CAS 1112-48-7) References

  1. Direct synthesis of bipyrroles using phenyliodine bis(trifluoroacetate) with bromotrimethylsilane.  |  Dohi, T., et al. 2006. Org Lett. 8: 2007-10. PMID: 16671768
  2. Fmoc-chemistry of a stable phosphohistidine analogue.  |  McAllister, TE., et al. 2011. Chem Commun (Camb). 47: 1297-9. PMID: 21103476
  3. Synthesis and properties of 1-(3'-dihydroxyboryl-2',3'-dideoxyribosyl)pyrimidines.  |  Kim, BJ., et al. 2012. Org Biomol Chem. 10: 9349-58. PMID: 23108312
  4. McKenna reaction--which oxygen attacks bromotrimethylsilane?  |  Błażewska, KM. 2014. J Org Chem. 79: 408-12. PMID: 24266500
  5. TMSBr-mediated solvent- and work-up-free synthesis of α-2-deoxyglycosides from glycals.  |  Hsu, MY., et al. 2016. Beilstein J Org Chem. 12: 1758-64. PMID: 27559420
  6. Phosphonic acid: preparation and applications.  |  Sevrain, CM., et al. 2017. Beilstein J Org Chem. 13: 2186-2213. PMID: 29114326
  7. Synthesis and Aqueous Solution Properties of an Amino Bisphosphonate Methacrylate Homopolymer via RAFT Polymerization.  |  Falireas, PG., et al. 2018. Polymers (Basel). 10: PMID: 30960636
  8. Polyglycidol-based metal adhesion promoters.  |  Koehler, J., et al. 2015. J Mater Chem B. 3: 804-813. PMID: 32262171
  9. Highly Enantioselective, Hydrogen-Bond-Donor Catalyzed Additions to Oxetanes.  |  Strassfeld, DA., et al. 2020. J Am Chem Soc. 142: 9175-9180. PMID: 32364378
  10. The McKenna reaction - avoiding side reactions in phosphonate deprotection.  |  Justyna, K., et al. 2020. Beilstein J Org Chem. 16: 1436-1446. PMID: 32647545
  11. One-Step Synthesis of Triphenylphosphonium Salts from (Het)arylmethyl Alcohols.  |  Chalikidi, PN., et al. 2021. J Org Chem. 86: 9838-9846. PMID: 34232646
  12. Iterative addition of carbon nucleophiles to N,N-dialkyl carboxamides for synthesis of α-tertiary amines.  |  Chen, J., et al. 2021. Chem Sci. 13: 99-104. PMID: 35059156
  13. Bromotrimethylsilane as a selective reagent for the synthesis of bromohydrins.  |  Giomi, D., et al. 2021. RSC Adv. 11: 14453-14458. PMID: 35424012
  14. Copper-Catalyzed Annulation-Trifluoromethyl Functionalization of Enynones.  |  Wang, JY., et al. 2023. Org Lett. 25: 2509-2514. PMID: 37010156

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bromotriethylsilane, 5 g

sc-227534
5 g
$245.00