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Bromotrichloromethane (CAS 75-62-7)

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Alternate Names:
Trichlorobromomethane
Application:
Bromotrichloromethane is a versatile reagent used in the bromination of active hydrogen compounds
CAS Number:
75-62-7
Purity:
97%
Molecular Weight:
198.27
Molecular Formula:
BrCCl3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bromotrichloromethane is a chain transfer agent for radical polymerization of methacrylates. Brominating reagent. Reagent for the bromination of active hydrogen compounds. Used for the preparation of a dichloromethylenephosphorane, a Wittig reagent.


Bromotrichloromethane (CAS 75-62-7) References

  1. Increased proteolysis after single-dose exposure with hepatotoxins in HepG2 cells.  |  Pirlich, M., et al. 2002. Free Radic Biol Med. 33: 283-91. PMID: 12106824
  2. Protein damage and lipid peroxidation: effects of diethyl maleate, bromotrichloromethane and vitamin E on ammonia, urea and enzymes involved in ammonia metabolism.  |  Park, JR. and Tappel, AL. 1991. Toxicol Lett. 58: 29-36. PMID: 1680252
  3. Biodehalogenation of bromotrichloromethane and 1,2-dibromo-3-chloropropane by Pseudomonas putida PpG-786.  |  Lam, T. and Vilker, VL. 1987. Biotechnol Bioeng. 29: 151-9. PMID: 18576369
  4. Histological evidence for dissociation of lipid peroxidation and cell necrosis in bromotrichloromethane hepatotoxicity in the perfused rat liver.  |  Masuda, Y. and Yamamori, Y. 1991. Jpn J Pharmacol. 56: 143-50. PMID: 1880993
  5. Molecular mechanisms for bromotrichloromethane cytotoxicity in isolated rat hepatocytes.  |  McGirr, LG., et al. 1990. Xenobiotica. 20: 933-43. PMID: 2238712
  6. Oxidant-induced haemoprotein degradation in rat tissue slices: effect of bromotrichloromethane, antioxidants and chelators.  |  Hidalgo, FJ., et al. 1990. Biochim Biophys Acta. 1037: 313-20. PMID: 2310747
  7. Bromotrichloromethane-induced damage to bronchiolar Clara cells.  |  Lungarella, G., et al. 1987. Res Commun Chem Pathol Pharmacol. 57: 213-28. PMID: 3659570
  8. Pathological mechanisms in carbon tetrachloride hepatotoxicity.  |  Brattin, WJ., et al. 1985. J Free Radic Biol Med. 1: 27-38. PMID: 3915301
  9. Hepatotoxicity of bromotrichloromethane--bond dissociation energy and lipoperoxidation.  |  Koch, RR., et al. 1974. Biochem Pharmacol. 23: 2907-15. PMID: 4429591
  10. The formation of diglutathionyl dithiocarbonate as a metabolite of chloroform, bromotrichloromethane, and carbon tetrachloride.  |  Pohl, LR., et al. 1981. Drug Metab Dispos. 9: 334-9. PMID: 6114833
  11. Carbon tetrachloride, bromotrichloromethane and ethanol acute intoxication. New chemical evidence for lipid peroxidation in rat tissue microsomes.  |  Corongiu, FP., et al. 1983. Biochem J. 212: 625-31. PMID: 6882388
  12. Oxidation of carbon tetrachloride, bromotrichloromethane, and carbon tetrabromide by rat liver microsomes to electrophilic halogens.  |  Mico, BA., et al. 1982. Life Sci. 30: 131-7. PMID: 7054640
  13. Evaluation of a role for phosgene production in the hepatotoxic mechanism of action of carbon tetrachloride and bromotrichloromethane.  |  Waller, RL. and Recknagel, RO. 1982. Toxicol Appl Pharmacol. 66: 172-81. PMID: 7164096

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bromotrichloromethane, 100 g

sc-252520
100 g
$77.00

Bromotrichloromethane, 500 g

sc-252520A
500 g
$111.00