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Bromopride (CAS 4093-35-0)

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Alternate Names:
Artomey; Valopride; Viaben
Application:
Bromopride is an antiemetic agent that acts as a D2DR (dopamine D2 receptor) antagonist
CAS Number:
4093-35-0
Molecular Weight:
344.25
Molecular Formula:
C14H22BrN3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bromopride is a compound that is of interest in the realm of biochemistry for its interaction with dopaminergic systems. Its primary focus in research is on the elucidation of pathways involving dopamine receptors and the modulation of dopamine levels in various organisms. Bromopride serves as a useful tool in studies aimed at understanding the mechanisms of action of dopamine antagonists. In addition, it is utilized in research on gastrointestinal motility due to its action on dopaminergic pathways that can influence the movement of the digestive tract. The compound is often used in assays to observe the effects of dopaminergic modulation on gut motility. Furthermore, Bromopride is studied within the context of its impact on the central nervous system and its potential to cross the blood-brain barrier.


Bromopride (CAS 4093-35-0) References

  1. Influence of bromopride in the prophylaxis of nausea associated with fluorescein angiography.  |  Lira, RP., et al. 2007. Arq Bras Oftalmol. 70: 105-8. PMID: 17505728
  2. Case-crossover study of Burkholderia cepacia complex bloodstream infection associated with contaminated intravenous bromopride.  |  Martins, IS., et al. 2010. Infect Control Hosp Epidemiol. 31: 516-21. PMID: 20205589
  3. Effects of bromopride on the healing of left colon anastomoses of rats.  |  Marques e Silva, S., et al. 2011. Rev Col Bras Cir. 38: 429-34. PMID: 22267142
  4. Metabolism of bromopride in mouse, rat, rabbit, dog, monkey, and human hepatocytes.  |  Dunne, CE., et al. 2013. Drug Metab Pharmacokinet. 28: 453-61. PMID: 23615565
  5. Sensitive flow-injection spectrophotometric analysis of bromopride.  |  Lima, LS., et al. 2014. Spectrochim Acta A Mol Biomol Spectrosc. 133: 597-604. PMID: 24992919
  6. Effects of bromopride on expression of metalloproteinases and interleukins in left colonic anastomoses: an experimental study.  |  Silva, SM., et al. 2014. Braz J Med Biol Res. 47: 911-6. PMID: 25140813
  7. Perinatal bromopride treatment: effects on sexual behavior of male and female rats.  |  Felicio, LF., et al. 1989. Behav Neural Biol. 52: 145-51. PMID: 2803170
  8. Perinatal bromopride treatment: effects on motor activity and stereotyped behavior of offspring.  |  Felício, LF., et al. 1989. Physiol Behav. 45: 1081-5. PMID: 2813531
  9. Population pharmacokinetics of orally administrated bromopride: Focus on the absorption process.  |  Lachi-Silva, L., et al. 2020. Eur J Pharm Sci. 142: 105081. PMID: 31669384
  10. Dopaminergic supersensitivity after long-term bromopride treatment.  |  Felicio, LF., et al. 1987. Physiol Behav. 41: 433-7. PMID: 3432396
  11. Stability-indicating method development for quantification of bromopride, its impurities, and degradation products by ultra-high performance liquid chromatography applying Analytical Quality by Design principles.  |  Abreu, JC., et al. 2021. J Pharm Biomed Anal. 205: 114306. PMID: 34385016
  12. Development of novel montmorillonite-based sustained release system for oral bromopride delivery.  |  Bello, ML., et al. 2022. Eur J Pharm Sci. 175: 106222. PMID: 35649471
  13. Pharmacokinetics and bioavailability of the anti-emetic agent bromopride.  |  Brodie, RR., et al. 1986. Biopharm Drug Dispos. 7: 215-22. PMID: 3730521
  14. Differential effects of bromopride and domperidone on cholinesterase activity in rat tissues.  |  Nasello, AG., et al. 1995. Life Sci. 56: 151-6. PMID: 7823770

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bromopride, 10 mg

sc-217793
10 mg
$188.00