Date published: 2025-10-3

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Bromoform (CAS 75-25-2)

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Alternate Names:
Tribromomethane
CAS Number:
75-25-2
Molecular Weight:
252.73
Molecular Formula:
CHBr3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bromoform is classified as a halogenated hydrocarbon and belongs to the group of brominated compounds called trihalomethanes. This compound serves as a widely employed industrial solvent and also finds applications as a chemical reagent in laboratory applications. In scientific research, bromoform holds diverse uses, including its role in the synthesis of organic compounds, its involvement in the detection and quantification of organic substances, and its contributions to the study of biochemical and physiological processes. Notably, bromoform has been utilized in synthesizing various organic compounds, such as steroids and terpenes. Moreover, it has been effectively employed to detect and quantify organic compounds using analytical techniques like gas chromatography and liquid chromatography.


Bromoform (CAS 75-25-2) References

  1. Ultrafast observation of isomerization and complexation in the photolysis of bromoform in solution.  |  Carrier, SL., et al. 2010. J Phys Chem A. 114: 1548-55. PMID: 19968312
  2. Bromoform reaction of tertiary amines with N,N-dibromosulfonamides or NBS/sulfonamides.  |  Chen, J., et al. 2014. Chem Commun (Camb). 50: 12367-70. PMID: 25187429
  3. Effect of trihalomethanes (chloroform and bromoform) on human haematological count.  |  Lodhi, A., et al. 2017. J Water Health. 15: 367-373. PMID: 28598341
  4. Double rarity: an unusual case of bromoform poisoning detected by post-mortem radiography.  |  du Plessis, M., et al. 2020. Int J Legal Med. 134: 703-708. PMID: 30848339
  5. Interpretation of the THz-THz-Raman Spectrum of Bromoform.  |  Magdău, IB., et al. 2019. J Phys Chem A. 123: 7278-7287. PMID: 31329439
  6. Natural and anthropogenic sources of bromoform and dibromomethane in the oceanographic and biogeochemical regime of the subtropical North East Atlantic.  |  Mehlmann, M., et al. 2020. Environ Sci Process Impacts. 22: 679-707. PMID: 32163052
  7. Bromoform, dibromochloromethane, and dibromomethane over the East China Sea and the western Pacific Ocean: Oceanic emission and spatial variation.  |  Liu, SS., et al. 2020. Chemosphere. 257: 127151. PMID: 32470539
  8. Obligate Brominating Enzymes Underlie Bromoform Production by Marine Cyanobacteria.  |  Thapa, HR. and Agarwal, V. 2021. J Phycol. 57: 1131-1139. PMID: 33556207
  9. Reaction of DMS and HOBr as a Sink for Marine DMS and an Inhibitor of Bromoform Formation.  |  Müller, E., et al. 2021. Environ Sci Technol. 55: 5547-5558. PMID: 33788559
  10. Deconstructing the Local Intermolecular Ordering and Dynamics of Liquid Chloroform and Bromoform.  |  Karnes, JJ. and Benjamin, I. 2021. J Phys Chem B. 125: 3629-3637. PMID: 33792320
  11. Safety and Transfer Study: Transfer of Bromoform Present in Asparagopsis taxiformis to Milk and Urine of Lactating Dairy Cows.  |  Muizelaar, W., et al. 2021. Foods. 10: PMID: 33802209
  12. Chromium-catalyzed cyclopropanation of alkenes with bromoform in the presence of 2,3,5,6-tetramethyl-1,4-bis(trimethylsilyl)-1,4-dihydropyrazine.  |  Ikeda, H., et al. 2020. Chem Sci. 11: 3604-3609. PMID: 34094048
  13. Relationship between Blood Trihalomethane Concentrations and Serum Thyroid Function Measures in U.S. Adults.  |  Sun, Y., et al. 2021. Environ Sci Technol. 55: 14087-14094. PMID: 34617747
  14. Underestimation of Anthropogenic Bromoform Released into the Environment?  |  Quivet, E., et al. 2022. Environ Sci Technol. 56: 1522-1533. PMID: 35037465
  15. Synthesis of 2-substituted bicyclo[1.1.0]butanes via zincocyclopropanation using bromoform as the carbenoid precursor.  |  Thai-Savard, L. and Charette, AB. 2023. Chem Commun (Camb). 59: 5273-5276. PMID: 37057670

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bromoform, 50 g

sc-239424
50 g
$82.00