Date published: 2026-4-3

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Bromochlorofluoroacetic acid (CAS 354-03-0)

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Alternate Names:
2-bromo-2-chloro-2-fluoroacetic acid
Application:
CAS Number:
354-03-0
Molecular Weight:
191.38
Molecular Formula:
C2HBrClFO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bromochlorofluoroacetic acid (BCFA) is a colorless, pungent-smelling liquid that falls under the category of halogenated acetic acids. Its unique properties make it a valuable component in scientific research. Bromochlorofluoroacetic acid is prepared through a series of steps, and the approach to its synthesis is a key part of its application in research. Bromochlorofluoroacetic acid is used mostly in scientific research as a reagent for determining the amino acid sequences in peptides and proteins. It also serves as a derivatizing agent for gas chromatography-mass spectrometry (GC-MS) analysis of organic compounds. Bromochlorofluoroacetic acid has found utility in an array of research areas, from biochemistry and pharmacology to toxicology. While the exact mechanism of action of Bromochlorofluoroacetic acid is not entirely clear, it′s theorized to interact with the amino groups of peptides and proteins, creating stable derivatives that can be evaluated through various techniques. Additionally, Bromochlorofluoroacetic acid is known to react with other organic compounds, including alcohols and carboxylic acids.


Bromochlorofluoroacetic acid (CAS 354-03-0) References

  1. Determination of absolute configuration using single crystal X-ray diffraction.  |  Albright, AL. and White, JM. 2013. Methods Mol Biol. 1055: 149-62. PMID: 23963909

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bromochlorofluoroacetic acid, 1 g

sc-300303
1 g
$200.00

Bromochlorofluoroacetic acid, 5 g

sc-300303A
5 g
$300.00