Date published: 2025-10-6

1-800-457-3801

SCBT Portrait Logo
Seach Input

Bromobenzene (CAS 108-86-1)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Phenyl bromide; Monobromobenzene
Application:
Bromobenzene is an aryl halide used to introduce a phenyl group
CAS Number:
108-86-1
Purity:
≥98%
Molecular Weight:
157.01
Molecular Formula:
C6H5Br
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Bromobenzene, also referred to as phenyl bromide, is an aromatic compound denoted by the chemical formula C6H5Br. This colorless and flammable liquid finds utility in synthesizing diverse organic compounds. In scientific research, bromobenzene assumes the role of a reagent in numerous applications. For instance, it contributes to the synthesis of diverse organic compounds like aromatic amines and aryl halides. Furthermore, bromobenzene plays a key role in the synthesis of dyes, pigments, and other chemical compounds. While the exact mechanism of action of bromobenzene remains incompletely understood, it is hypothesized that the bromine atom within the molecule undergoes a reaction with the benzene ring, leading to the formation of a bromonium ion.


Bromobenzene (CAS 108-86-1) References

  1. Bromobenzene-induced hepatotoxicity at the transcriptome level.  |  Heijne, WH., et al. 2004. Toxicol Sci. 79: 411-22. PMID: 15056800
  2. Bromobenzene metabolism in vivo and in vitro. The mechanism of 4-bromocatechol formation.  |  Miller, NE., et al. 1990. Drug Metab Dispos. 18: 304-8. PMID: 1974190
  3. Bromobenzene flame retardants in the Great Lakes atmosphere.  |  Venier, M., et al. 2012. Environ Sci Technol. 46: 8653-60. PMID: 22849422
  4. Bromobenzene-mediated alteration in activity and electrophoretic pattern of biliverdin reductase variants in rat kidney.  |  Huang, TJ. and Maines, MD. 1990. Mol Pharmacol. 37: 25-9. PMID: 2300045
  5. Bromobenzene-induced lethal toxicity in mouse is prevented by pretreatment with zinc sulfate.  |  Yoshioka, H., et al. 2016. Chem Biol Interact. 254: 117-23. PMID: 27270452
  6. Chronotoxicity of bromobenzene-induced hepatic injury in mice.  |  Yoshioka, H., et al. 2017. J Toxicol Sci. 42: 251-258. PMID: 28321051
  7. Bromobenzene metabolism in the rat and guinea pig.  |  Lertratanangkoon, K. and Horning, MG. 1987. Drug Metab Dispos. 15: 1-11. PMID: 2881744
  8. The contribution of bromobenzene to our current understanding of chemically-induced toxicities.  |  Lau, SS. and Monks, TJ. 1988. Life Sci. 42: 1259-69. PMID: 3280935
  9. Different Hepatic Concentrations of Bromobenzene, 1,2-Dibromobenzene, and 1,4-Dibromobenzene in Humanized-Liver Mice Predicted Using Simplified Physiologically Based Pharmacokinetic Models as Putative Markers of Toxicological Potential.  |  Miura, T., et al. 2020. Chem Res Toxicol. 33: 3048-3053. PMID: 33283517
  10. Different Renal Chronotoxicity of Bromobenzene and Its Intermediate Metabolites in Mice.  |  Yoshioka, H., et al. 2021. Biol Pharm Bull. 44: 150-153. PMID: 33390544
  11. Nephrotoxicity of bromobenzene in mice.  |  Rush, GF., et al. 1984. Toxicol Lett. 20: 23-32. PMID: 6695393
  12. Bromobenzene and p-bromophenol toxicity and covalent binding in vivo.  |  Monks, TJ., et al. 1982. Life Sci. 30: 841-8. PMID: 7070199
  13. Bromobenzene epoxidation leading to binding on macromolecular protein sites.  |  Lau, SS. and Zannoni, VG. 1981. J Pharmacol Exp Ther. 219: 563-72. PMID: 7288634
  14. Bromobenzene detoxification in the human liver-derived HepG2 cell line.  |  Duthie, SJ., et al. 1994. Xenobiotica. 24: 265-79. PMID: 8009889

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bromobenzene, 100 ml

sc-214628
100 ml
$29.00

Bromobenzene, 500 ml

sc-214628A
500 ml
$86.00