Bromoacetylcholine bromide (CAS 22004-27-9)

This chemical is characterized by the presence of a bromoacetyl group attached to the nitrogen atom of choline, along with a bromide ion as its counterion. Its molecular structure combines elements of acetylcholine with an added bromine atom, resulting in a compound that retains the quaternary ammonium group characteristic of choline derivatives, but with increased reactivity due to the bromoacetyl moiety. In terms of its physical appearance, bromoacetylcholine bromide is typically presented as a white or off-white crystalline solid. The bromoacetyl group significantly alters its chemical properties compared to acetylcholine, making it more reactive, particularly in organic synthesis and chemical reactions where the bromine atom can act as a leaving group or participate in nucleophilic substitution reactions. The compound finds its use primarily in biochemical research and chemical synthesis. In research applications, it can be employed in the study of biochemical pathways involving acetylcholine or as a precursor for synthesizing more complex molecules. Its reactivity with nucleophiles, and the potential to form stable covalent bonds with biological molecules, makes it useful in the synthesis of chemical probes or in the modification of biomolecules for analytical purposes.