Brimonidine Tartrate CAS: 70359-46-5
MF: C15H16BrN5O6
Brimonidine Tartrate is an α-2 receptor agonist.

Brimonidine Tartrate (CAS 70359-46-5)

Brimonidine Tartrate | CAS 70359-46-5 is rated 5.0 out of 5 by 1.
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Alternate Names: 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine tartrate
Application: Brimonidine Tartrate is an α-2 receptor agonist
CAS Number: 70359-46-5
Purity: ≥99%
Molecular Weight: 442.22
Molecular Formula: C15H16BrN5O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Brimonidine Tartrate is an AR (α 2 receptor) agonist used to treat glaucoma and acts via decreasing aqueous humor synthesis.


References

Katz, L.J., et al.: Am. J. Ophthalmol., 127, 20 (1999) Cantor, L. B., Expert Opin. Pharmacother., 1, 815 (2000)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in DMSO, methanol, and water (50 mM).
Storage :
Store at -20° C
Melting Point :
207-208° C (dec.)
Boiling Point :
432.6° C at 760 mmHg
Refractive Index :
n20D 1.80 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
VD1200000
PubChem CID :
11236066
Merck Index :
14: 1375
MDL Number :
MFCD07773072
SMILES :
C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br.C(C(C(=O)O)O)(C(=O)O)O

Download SDS (MSDS)

Certificate of Analysis

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Brimonidine Tartrate (CAS 70359-46-5)  Product Citations

See how others have used Brimonidine Tartrate (CAS 70359-46-5). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 24983144  Fedorchak, MV. et al. 2014. Experimental eye research. 125: 210-6.

PMID: # 24080317  Mealy, JE. et al. 2014. Acta biomaterialia. 10: 87-93.

PMID: # 27463221  J Ocul Pharmacol Ther. 32: 405-14.

Citations 1 to 3 of 3 total

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. The compound, sc-217788, is provided as a white crystalline powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-01-12
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Rated 5 out of 5 by from Harun Harun-Or-Rashid, M. et al. (PubMed 26377080) found that 2-adrenergic receptor ( 2R) stimulation via the 2R agonsit Brimonidine Tartrate attenuated injury-induced ERK activation and dedifferentiation of M ller cells as seen by decreased phospho-ERK, expression of transitin, and retinal progenitor cell genes. -SCBT Publication Review
Date published: 2015-05-16
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