Date published: 2025-9-21

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Bradykinin (CAS 58-82-2)

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Datasheets
CAS Number:
58-82-2
Molecular Weight:
1060.2
Molecular Formula:
C50H73N15O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Supplied as an acetate salt. HYGROSCOPIC. Induces the release of nitric oxide. Other physiological functions include stimulation of pain receptors, inhibition of cAMP accumulation, and induction of smooth muscle contraction and vasodilation. Also involved in edema resulting from trauma or injury. Improves post-ischemic recovery of heart via a nitric oxide-dependent mechanism.RTECS EE1530000 Merck Index: 14, 1359


Bradykinin (CAS 58-82-2) References

  1. Effect of bradykinin on isolated mesenteric arteries of the rat.  |  Salgado, MC., et al. 1992. Hypertension. 19: II251-4. PMID: 1735587
  2. Quantitative assay for bradykinin in rat plasma by liquid chromatography coupled to tandem mass spectrometry.  |  Baralla, E., et al. 2011. J Pharm Biomed Anal. 54: 557-61. PMID: 21030179
  3. Receptors and mechanisms mediating the biphasic response evoked by bradykinin in rat colonic smooth muscle.  |  Würner, L. and Diener, M. 2013. Neurogastroenterol Motil. 25: e581-90. PMID: 23742018
  4. Intratesticular Bradykinin Involvement in Rat Testicular Pain Models.  |  Fujimoto, K., et al. 2018. Low Urin Tract Symptoms. 10: 101-105. PMID: 27167873
  5. Excitatory effect of bradykinin on intrinsic neurons of the rat heart.  |  Arichi, S., et al. 2019. Neuropeptides. 75: 65-74. PMID: 31047706
  6. Bradykinin Activates the Bradykinin B2 Receptor to Ameliorate Neuronal Injury in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury.  |  Yang, G., et al. 2021. ACS Chem Neurosci. 12: 1031-1038. PMID: 33621043
  7. Presystemic bradykinin metabolism in sheep and rat nasal homogenates.  |  Chung, FY. and Donovan, MD. 1995. J Pharm Sci. 84: 794-8. PMID: 7562426
  8. Inflammation modulates the contribution of receptor-subtypes to bradykinin-induced hyperalgesia in the rat.  |  Khasar, SG., et al. 1995. Neuroscience. 69: 685-90. PMID: 8552260
  9. Bradykinin metabolism in the liver and lung of the rat.  |  Griswold, JA., et al. 1996. J Surg Res. 66: 12-20. PMID: 8954825
  10. Bradykinin stimulates prepubertal rat germ cell proliferation in vitro.  |  Atanassova, N., et al. 1998. Immunopharmacology. 40: 173-8. PMID: 9858060

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bradykinin, 5 mg

sc-507311
5 mg
$110.00