Molecular structure of BPIQ-I, CAS Number: 174709-30-9
BPIQ-I (CAS 174709-30-9)
Alternate Names:
8-[(3-Bromophenyl)amino]-3-methyl-3H-imidazo[4,5-g]-quinazoline
Application:
BPIQ-I is a potent and specific inhibitor of tyrosine kinase activity of EGFR
CAS Number:
174709-30-9
Molecular Weight:
354.2
Molecular Formula:
C16H12BrN5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
BPIQ-I, a newly developed synthetic peptide. Its utilization encompasses a wide range of experiments, from evaluating the influence of peptides on cell growth to unraveling the role of peptides in gene expression regulation. Noteworthy is the unique nature of BPIQ-I, allowing it to interact with diverse cell types. While the complete mechanism of action of BPIQ-I remains elusive, it is believed to operate through multiple pathways. One proposed mode involves interaction with cells via various receptors, modulating the activity of intracellular signaling molecules. Furthermore, BPIQ-I is speculated to engage with specific transcription factors responsible for gene expression regulation.
BPIQ-I (CAS 174709-30-9) References
- Delta-opioid receptors activate ERK/MAP kinase via integrin-stimulated receptor tyrosine kinases. | Eisinger, DA. and Ammer, H. 2008. Cell Signal. 20: 2324-31. PMID: 18804531
- Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor. | Rewcastle, GW., et al. 1996. J Med Chem. 39: 918-28. PMID: 8632415
Inhibitor of:
EGFR, and Tyrosine Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BPIQ-I, 1 mg | sc-202507 | 1 mg | $153.00 |