Molecular structure of BPDQ, CAS Number: 169205-87-2
BPDQ (CAS 169205-87-2)
Application:
BPDQ is a potent, reversible, and specific inhibitor of EGFR tyrosine kinase
CAS Number:
169205-87-2
Molecular Weight:
330.2
Molecular Formula:
C14H12BrN5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
A cell-permeable, reversible, ATP-competitive, potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 120 pM).
BPDQ (CAS 169205-87-2) References
- Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-[(phenylmethyl)amino]- and 4-(phenylamino)quinazolines as potent adenosine 5'-triphosphate binding site inhibitors of the tyrosine kinase domain of the epidermal growth factor receptor. | Rewcastle, GW., et al. 1995. J Med Chem. 38: 3482-7. PMID: 7658435
- Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor. | Rewcastle, GW., et al. 1996. J Med Chem. 39: 918-28. PMID: 8632415
Inhibitor of:
EGFR, and Tyrosine Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BPDQ, 1 mg | sc-311299 | 1 mg | $160.00 |