Molecular structure of Bourgeonal, CAS Number: 18127-01-0
Bourgeonal (CAS 18127-01-0)
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Alternate Names:
4-(1,1-Dimethylethyl)benzenepropanal
Application:
Bourgeonal is a potent hOR17-4 receptor agonist
CAS Number:
18127-01-0
Purity:
≥90%
Molecular Weight:
190.28
Molecular Formula:
C13H18O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A potent agonist at hOR17-4 (a human testicular olfactory receptor) that acts as a strong chemoattractant in sperm behavioral assays.
Bourgeonal (CAS 18127-01-0) References
- Identification of a testicular odorant receptor mediating human sperm chemotaxis. | Spehr, M., et al. 2003. Science. 299: 2054-8. PMID: 12663925
- Chirality and fragrance chemistry: stereoisomers of the commercial chiral odorants Muguesia and Pamplefleur. | Abate, A., et al. 2005. J Org Chem. 70: 1281-90. PMID: 15704962
- Odorant receptors and olfactory-like signaling mechanisms in mammalian sperm. | Spehr, M., et al. 2006. Mol Cell Endocrinol. 250: 128-36. PMID: 16413109
- Prediction of perception: probing the hOR17-4 olfactory receptor model with silicon analogues of bourgeonal and lilial. | Doszczak, L., et al. 2007. Angew Chem Int Ed Engl. 46: 3367-71. PMID: 17397127
- Control of sperm motility and fertility: diverse factors and common mechanisms. | Yoshida, M., et al. 2008. Cell Mol Life Sci. 65: 3446-57. PMID: 18622578
- Large-scale production and study of a synthetic G protein-coupled receptor: human olfactory receptor 17-4. | Cook, BL., et al. 2009. Proc Natl Acad Sci U S A. 106: 11925-30. PMID: 19581598
- Odor interaction between Bourgeonal and its antagonist undecanal. | Brodin, M., et al. 2009. Chem Senses. 34: 625-30. PMID: 19620388
- Designing exons for human olfactory receptor gene subfamilies using a mathematical paradigm. | Hassan, SS., et al. 2010. J Biosci. 35: 389-93. PMID: 20826948
- Chemosensory Ca2+ dynamics correlate with diverse behavioral phenotypes in human sperm. | Veitinger, T., et al. 2011. J Biol Chem. 286: 17311-25. PMID: 21454470
- Ultra-high olfactory sensitivity for the human sperm-attractant aromatic aldehyde bourgeonal in CD-1 mice. | Larsson, L. and Laska, M. 2011. Neurosci Res. 71: 355-60. PMID: 21893110
- Novel bourgeonal fragrance conjugates for the detection of prostate cancer. | Sturzu, A., et al. 2013. Invest New Drugs. 31: 1151-7. PMID: 23508273
- Olfactory Receptors Modulate Physiological Processes in Human Airway Smooth Muscle Cells. | Kalbe, B., et al. 2016. Front Physiol. 7: 339. PMID: 27540365
- Olfaction, taste and chemoreception: scientific evidence replaces 'Essays in biopoetry'. | Appendino, G., et al. 2017. Nat Prod Rep. 34: 469-471. PMID: 28485741
- Incorporating integrated testing strategy (ITSv1) defined approach into read-across (RAx) in predicting skin sensitization potency: ITSv1-based RAx. | Nakayama, K., et al. 2023. Regul Toxicol Pharmacol. 139: 105358. PMID: 36805910
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OR1D2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bourgeonal, 10 mg | sc-210959 | 10 mg | $306.00 | |||
Bourgeonal, 100 mg | sc-210959A | 100 mg | $1102.00 |