Borrelia burgdorferi sensu stricto Antibody (Bss98): sc-51787

Borrelia burgdorferi sensu stricto Antibody (Bss98) is a mouse monoclonal IgG2b antibody that detects Borrelia burgdorferi sensu stricto by western blotting (WB) and immunofluorescence (IF). Borrelia burgdorferi sensu stricto is a crucial pathogen responsible for Lyme disease, a multisystem inflammatory condition that can lead to severe health complications if left untreated. This spirochete is known for its unique ability to undergo extensive genetic exchange, including plasmid transfers, which contributes to its rapid adaptive evolution and potential pathogenicity. The frequent recombination events within its genome not only enhance its survival in diverse environments but also allow it to evade the host′s immune response, making it a formidable challenge in clinical settings. Understanding the dynamics of Borrelia burgdorferi sensu stricto′s genetic variability is essential for developing effective diagnostic tools and therapeutic strategies against Lyme disease. Anti-Borrelia burgdorferi sensu stricto antibody (Bss98) is an invaluable resource for researchers studying this complex pathogen and its interactions within the host.

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Borrelia burgdorferi sensu stricto Antibody (Bss98) References:

1. Borrelia burgdorferi sensu stricto invasiveness is correlated with OspC-plasminogen affinity.  |  Lagal, V., et al. 2006. Microbes Infect. 8: 645-52. PMID: 16513394
2. Confirmation of Borrelia burgdorferi sensu stricto and Anaplasma phagocytophilum in Ixodes scapularis, Southwestern Virginia.  |  Herrin, BH., et al. 2014. Vector Borne Zoonotic Dis. 14: 821-3. PMID: 25409274
3. Borrelia burgdorferi Infection in Biglycan Knockout Mice.  |  Cuellar, J., et al. 2019. J Infect Dis. 220: 116-126. PMID: 30698707
4. Passerine birds as hosts for Ixodes ticks infected with Borrelia burgdorferi sensu stricto in southeastern Virginia.  |  Cumbie, AN., et al. 2021. Ticks Tick Borne Dis. 12: 101650. PMID: 33486431
5. Predicting distributions of blacklegged ticks (Ixodes scapularis), Lyme disease spirochetes (Borrelia burgdorferi sensu stricto) and human Lyme disease cases in the eastern United States.  |  Burtis, JC., et al. 2022. Ticks Tick Borne Dis. 13: 102000. PMID: 35785605
6. Outer surface protein E (OspE) mediates Borrelia burgdorferi sensu stricto strain-specific complement evasion in the eastern fence lizard, Sceloporus undulatus.  |  Nowak, TA., et al. 2023. Ticks Tick Borne Dis. 14: 102081. PMID: 36403322
7. Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia.  |  Berthold, A., et al. 2022. J Vis Exp.. PMID: 36504091
8. Detection of Borrelia burgdorferi sensu lato species in host-seeking Ixodes species ticks in the United States.  |  Osikowicz, LM., et al. 2024. Ticks Tick Borne Dis. 15: 102270. PMID: 37813001
9. Possible effect of mutations on serological detection of Borrelia burgdorferi sensu stricto ospC major groups: An in-silico study.  |  Mechai, S., et al. 2023. PLoS One. 18: e0292741. PMID: 37815990
10. A novel panel of peptides with diagnostic potential for serological identification of Borrelia burgdorferi sensu stricto, B. garinii and B. afzelii in human sera.  |  Foddai, ACG., et al. 2025. J Immunol Methods. 536: 113802. PMID: 39793694