Borrelia burgdorferi garinii Antibody (Bg14): sc-51785

Borrelia burgdorferi garinii Antibody (Bg14) is a mouse monoclonal IgG1 antibody that detects Borrelia burgdorferi garinii protein by western blotting (WB) and immunofluorescence (IF). Anti-Borrelia burgdorferi garinii antibody (Bg14) is available as a non-conjugated format. Borrelia burgdorferi garinii protein plays a crucial role in Lyme disease pathogenesis, a vector-borne illness caused by spirochete Borrelia burgdorferi, transmitted to humans through Ixodes ricinus complex tick bites. Among various B. burgdorferi species, B. garinii is particularly significant as one of two major European strains, characterized by gram-negative and helical structure. B. garinii causes neurological symptoms in infected individuals, including back and leg pain and partial facial paralysis, primarily due to presence in mammalian cerebrospinal fluid. B. garinii interaction with neuronal cells occurs through outer surface protein A and cell-bound proteoglycans, essential for attachment and pathogenicity. Patients infected with B. garinii are typically older, showing trunk skin lesions, and experience shorter incubation periods compared to other Borrelia strains, resulting in higher rates of local systemic symptoms and abnormal liver function.

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Borrelia burgdorferi garinii Antibody (Bg14) References:

1. In vitro susceptibility testing of four antibiotics against Borrelia burgdorferi: a comparison of results for the three genospecies Borrelia afzelii, Borrelia garinii, and Borrelia burgdorferi sensu stricto.  |  Sicklinger, M., et al. 2003. J Clin Microbiol. 41: 1791-3. PMID: 12682190
2. Characteristics of erythema migrans in Borrelia afzelii and Borrelia garinii infections.  |  Carlsson, SA., et al. 2003. Scand J Infect Dis. 35: 31-3. PMID: 12685881
3. Association of Borrelia garinii and B. valaisiana with songbirds in Slovakia.  |  Hanincová, K., et al. 2003. Appl Environ Microbiol. 69: 2825-30. PMID: 12732554
4. Effect of the salivary gland and midgut extracts from Ixodes ricinus and Dermacentor reticulatus (Acari: Ixodidae) on the growth of Borrelia garinii in vitro.  |  Rudolf, I. and Hubálek, Z. 2003. Folia Parasitol (Praha). 50: 159-60. PMID: 14560980
5. Ability of Ixodes persulcatus, Haemaphysalis concinna and Dermacentor silvarum ticks to acquire and transstadially transmit Borrelia garinii.  |  Sun, Y. and Xu, R. 2003. Exp Appl Acarol. 31: 151-60. PMID: 14756409
6. Comparative analysis of the Borrelia garinii genome.  |  Glöckner, G., et al. 2004. Nucleic Acids Res. 32: 6038-46. PMID: 15547252
7. Comparison of growth of Borrelia afzelii, B. garinii, and B. burgdorferi sensu stricto in MKP and BSK-II medium.  |  Ruzić-Sabljić, E. and Strle, F. 2004. Int J Med Microbiol. 294: 407-12. PMID: 15595391
8. Adhesion of Borrelia garinii to neuronal cells is mediated by the interaction of OspA with proteoglycans.  |  Rupprecht, TA., et al. 2006. J Neuroimmunol. 175: 5-11. PMID: 16603253
9. Enhanced culture of Borrelia garinii and Borrelia afzelii strains on a solid BSK-based medium in anaerobic conditions.  |  De Martino, SJ., et al. 2006. Res Microbiol. 157: 726-9. PMID: 16814991

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Borrelia burgdorferi garinii Antibody (Bg14) has 1 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Borrelia burgdorferi garinii Antibody (Bg14) Specifications

Alternate Product Name: Borrelia burgdorferi garinii

Product Clone Name: Bg14

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Borrelia burgdorferi garinii

Epitope Species: Borrelia burgdorferi garinii

Product Reactivity/Detection: Borrelia burgdorferi garinii

Species Reactivity/Detection: Borrelia burgdorferi garinii

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Borrelia burgdorferi garinii Antibody (Bg14): N/A