Bordetella pertussis toxin (CAS 70323-44-3)
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Bordetella pertussis toxin is a multifunctional virulence factor that is extensively studied for its role in disrupting host immune responses. The research on this toxin delves into its ability to catalyze the ADP-ribosylation of G protein-coupled receptors, which alters signaling pathways within host cells. This disruption is key to understanding the modulation of immune cell function and the pathogenesis of whooping cough. Bordetella pertussis toxin also serves as a valuable probe in the study of intracellular signaling, particularly the regulation of adenylate cyclase and the resulting changes in cyclic AMP concentrations. Investigations involving the toxin provide insights into its contribution to the evasion of host defenses and the mechanisms by which it promotes bacterial survival and colonization. Additionally, Bordetella pertussis toxin is for examining the interactions between bacterial pathogens and the respiratory tract, offering a better understanding of respiratory infections and their complications.
Bordetella pertussis toxin (CAS 70323-44-3) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bordetella pertussis toxin, 50 µg | sc-471083 | 50 µg | $441.00 |