Date published: 2026-5-18

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Borage oil from Borago officinalis seeds (CAS 84012-16-8)

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CAS Number:
84012-16-8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Borage oil from Borago officinalis seeds functions as a source of gamma-linolenic acid (GLA) in experimental applications. It acts by incorporating into cell membranes and influencing the production of prostaglandins, which are lipid compounds involved in various physiological processes. Borage oil′s GLA content serves as a precursor for the synthesis of prostaglandin E1, which plays a role in regulating inflammation, immune function, and smooth muscle tone. By modulating prostaglandin production, borage oil may impact cellular signaling pathways and gene expression, potentially influencing various biological processes. At the molecular level, borage oil′s GLA content interacts with enzymes involved in prostaglandin synthesis, leading to alterations in the composition and function of cell membranes. Borage Oil From Borago Officinalis Seeds′s mechanism of action involves influencing lipid metabolism and the inflammatory response, potentially affecting cellular function and signaling pathways in experimental applications.


Borage oil from Borago officinalis seeds (CAS 84012-16-8) References

  1. Comparison of growth, serum biochemistries and n-6 fatty acid metabolism in rats fed diets supplemented with high-gamma-linolenic acid safflower oil or borage oil for 90 days.  |  Tso, P., et al. 2012. Food Chem Toxicol. 50: 1911-9. PMID: 22265940
  2. Antiasthmatic effects of gamma linolenic acid -high dose Evening Primrose Oil and Borage Oil stimulate allergen tachyphylaxis of sensitized guinea pigs and prevent allergen sensitization.  |  Dorsch, W. and Schmidt, O. 1995. Phytomedicine. 1: 271-5. PMID: 23196013
  3. Oral evening primrose oil and borage oil for eczema.  |  Bamford, JT., et al. 2013. Cochrane Database Syst Rev. 2013: CD004416. PMID: 23633319
  4. Intravenous fish oil in adult intensive care unit patients.  |  Heller, AR. 2015. World Rev Nutr Diet. 112: 127-40. PMID: 25471809
  5. Borage oil attenuates progression of cardiac remodeling in rats after myocardial infarction.  |  Maldonado-Menetti, Jdos S., et al. 2016. Acta Cir Bras. 31: 190-7. PMID: 27050790
  6. Microencapsulation of borage oil with blends of milk protein, β-glucan and maltodextrin through spray drying: physicochemical characteristics and stability of the microcapsules.  |  Li, RY. and Shi, Y. 2018. J Sci Food Agric. 98: 896-904. PMID: 28686292
  7. Borage oil restores acidic skin pH by up-regulating the activity or expression of filaggrin and enzymes involved in epidermal lactate, free fatty acid, and acidic free amino acid metabolism in essential fatty acid-deficient Guinea pigs.  |  Kim, KP., et al. 2018. Nutr Res. 58: 26-35. PMID: 30340812
  8. Role of Borage Seed Oil and Fish Oil with or without Turmeric and Alpha- Tocopherol in Prevention of Cardiovascular Disease and Fatty Liver in Rats.  |  Al-Okbi, SY., et al. 2018. J Oleo Sci. 67: 1551-1562. PMID: 30429440
  9. Borage Oil Enhances Lamellar Body Content and Alters Fatty Acid Composition of Epidermal Ceramides in Essential Fatty Acid-Deficient Guinea Pigs.  |  Kim, KP., et al. 2021. Lipids. 56: 345-353. PMID: 33378788
  10. Dietary borage oil alters plasma, hepatic and vascular tissue fatty acid composition in spontaneously hypertensive rats.  |  Engler, MM. and Engler, MB. 1998. Prostaglandins Leukot Essent Fatty Acids. 59: 11-5. PMID: 9758202

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Borage oil from Borago officinalis seeds, 100 g

sc-214618
100 g
$205.00