Molecular structure of BOP, CAS Number: 56602-33-6
BOP (CAS 56602-33-6)
Alternate Names:
(Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; Castros reagent
Application:
BOP is a useful reagent for peptide coupling, esterification of carboxilic acids and other research uses
CAS Number:
56602-33-6
Molecular Weight:
442.28
Molecular Formula:
C12H22N6OP•PF6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
BOP is primarily known as a peptide coupling reagent. It is additionally useful for the synthesis of esters, synthesis of magnolamide for antioxidative activity, and esterification of carboxylic acids. BOP, a novel phosphonium salt, serves as a valuable reagent. Its utility extends to the preparation of catalysts and catalytic systems, facilitating their synthesis. Moreover, BOP finds significance in the synthesis of polymers.
BOP (CAS 56602-33-6) References
- Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products. | Akula, HK., et al. 2017. Org Biomol Chem. 15: 1130-1139. PMID: 28054092
- Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products. | Akula, HK., et al. 2017. Org Biomol Chem. 15: 1268. PMID: 28101554
- Plaque-induced gingivitis: Case definition and diagnostic considerations. | Trombelli, L., et al. 2018. J Periodontol. 89 Suppl 1: S46-S73. PMID: 29926936
- Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate. | Akula, HK. and Lakshman, MK. 2019. Curr Protoc Nucleic Acid Chem. 76: e73. PMID: 30688408
- Synthesis and Antibacterial Activity of Difluoromethyl Cinnamoyl Amides. | Martínez, MD., et al. 2020. Molecules. 25: PMID: 32059479
- Protein synthesis with conformationally constrained cyclic dipeptides. | Zhang, C., et al. 2020. Bioorg Med Chem. 28: 115780. PMID: 33007560
- New Zileuton-Hydroxycinnamic Acid Hybrids: Synthesis and Structure-Activity Relationship towards 5-Lipoxygenase Inhibition. | Chiasson, AI., et al. 2020. Molecules. 25: PMID: 33066378
- Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria. | Naclerio, GA., et al. 2020. RSC Med Chem. 11: 102-110. PMID: 33479609
- Engineering a naturally derived hemostatic sealant for sealing internal organs. | Baghdasarian, S., et al. 2022. Mater Today Bio. 13: 100199. PMID: 35028556
- Cavitation assisted endoplasmic reticulum targeted sonodynamic droplets to enhanced anti-PD-L1 immunotherapy in pancreatic cancer. | Chen, J., et al. 2022. J Nanobiotechnology. 20: 283. PMID: 35710424
- A Straightforward Access to New Amides of the Melanin Precursor 5,6-Dihydroxyindole-2-carboxylic Acid and Characterization of the Properties of the Pigments Thereof. | Argenziano, R., et al. 2022. Molecules. 27: PMID: 35956765
- Covalent Inhibition of Pyruvate Kinase M2 Reprograms Metabolic and Inflammatory Pathways in Hepatic Macrophages against Non-alcoholic Fatty Liver Disease. | Fan, N., et al. 2022. Int J Biol Sci. 18: 5260-5275. PMID: 36147457
- Synthesis and Evaluation of Polymyxins Bearing Reductively Labile Disulfide-Linked Lipids. | Slingerland, CJ., et al. 2022. J Med Chem. 65: 15878-15892. PMID: 36399613
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BOP, 1 g | sc-221374 | 1 g | $20.00 | |||
BOP, 5 g | sc-221374A | 5 g | $62.00 |