Boc-Lys-OMe.HCl (CAS 55757-60-3)
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Boc-Lys-OMe.HCl is used in solution phase peptide synthesis. Boc-Lys-OMe.HCl, or N-tert-butoxycarbonyl-L-lysine methyl ester hydrochloride, is a chemically protected form of the amino acid lysine. The tert-butoxycarbonyl group is a protective group used to prevent the amino group on lysine from reacting during the peptide chain assembly process. The methyl ester modifies the carboxyl group at the other end of the lysine, also to prevent undesired reactions. The presence of the hydrochloride salt enhances the compound′s solubility in certain solvents, making it more manageable for use in laboratory applications. This specific form of lysine is valuable in the stepwise construction of peptides, allowing for the sequential addition of amino acids without interference from reactive side groups. Once the peptide synthesis is complete, the protective groups can be removed under specific conditions, yielding the desired peptide.
Boc-Lys-OMe.HCl (CAS 55757-60-3) References
- A continuous fluorimetric assay for aminopeptidase P detailed analysis of product inhibition. | Stöckel-Maschek, A., et al. 2003. Anal Biochem. 322: 60-7. PMID: 14705781
- Synthesis, characterization, and evaluation of ionizable lysine-based lipids for siRNA delivery. | Walsh, CL., et al. 2013. Bioconjug Chem. 24: 36-43. PMID: 23176544
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Boc-Lys-OMe.HCl, 1 g | sc-300288 | 1 g | $102.00 | |||
Boc-Lys-OMe.HCl, 5 g | sc-300288A | 5 g | $367.00 |