Boc-Lys(Fmoc)-OH (CAS 84624-27-1)
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Boc-Lys(Fmoc)-OH is a compound used as a building block in peptide synthesis. It functions as a protecting group for the lysine amino acid, preventing unwanted reactions during the peptide assembly process. Boc-Lys(Fmoc)-Oh is used in solid-phase peptide synthesis, where it is attached to a solid support and serves as a starting point for the stepwise addition of amino acids. Boc-Lys(Fmoc)-OH interacts with the amino and carboxyl groups of the lysine residue, allowing for controlled and selective deprotection and coupling reactions. Boc-Lys(Fmoc)-Oh′s mechanism of action involves the temporary masking of the lysine side chain, ensuring that the desired peptide sequence is assembled in a precise and controlled manner. Its role in peptide synthesis is to facilitate the creation of custom peptides with specific sequences and functionalities, contributing to the advancement of research in various fields such as biochemistry and molecular biology.
Boc-Lys(Fmoc)-OH (CAS 84624-27-1) References
- Synthesis of novel unnatural amino acid as a building block and its incorporation into an antimicrobial peptide. | Oh, JE. and Lee, KH. 1999. Bioorg Med Chem. 7: 2985-90. PMID: 10658605
- Cytotoxic analog of somatostatin containing methotrexate inhibits growth of MIA PaCa-2 human pancreatic cancer xenografts in nude mice. | Radulovic, S., et al. 1992. Cancer Lett. 62: 263-71. PMID: 1317746
- Self-assembled peptide amphiphile nanofibers conjugated to MRI contrast agents. | Bull, SR., et al. 2005. Nano Lett. 5: 1-4. PMID: 15792402
- pH and temperature-sensitive N-isopropylacrylamide ampholytic networks incorporating L-lysine. | Karbarz, M., et al. 2006. Langmuir. 22: 7843-7. PMID: 16922572
- Synthesis and biological activity of homoarginine-containing opioid peptides. | Izdebski, J., et al. 2007. J Pept Sci. 13: 27-30. PMID: 16967435
- Chimeric multiple antigenic peptides for simultaneous detection of specific antibodies to HIV-1 groups M, N, O, and HIV-2. | Pau, CP., et al. 2007. J Immunol Methods. 318: 59-64. PMID: 17169369
- Characterization of new multimeric erythropoietin receptor agonists. | Vadas, O., et al. 2008. Biopolymers. 90: 496-502. PMID: 18273892
- Inhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation. | Handlogten, MW., et al. 2013. Nat Chem Biol. 9: 789-95. PMID: 24096304
- Boc-SPPS: Compatible Linker for the Synthesis of Peptide o-Aminoanilides. | Weidmann, J., et al. 2016. Org Lett. 18: 164-7. PMID: 26702477
- Water-Soluble Polyglycerol Dendrimers with Two Orthogonally Reactive Core Functional Groups for One-Pot Functionalization. | Yang, SK. and Zimmerman, SC. 2015. Macromolecules. 48: 2504-2508. PMID: 27053818
- Solid-phase synthesis provides a modular, lysine-based platform for fluorescent discrimination of nitroxyl and biological thiols. | Loas, A., et al. 2015. Chem Sci. 6: 4131-4140. PMID: 28717469
- Branched pentapeptides as potent inhibitors of the vascular endothelial growth factor 165 binding to Neuropilin-1: Design, synthesis and biological activity. | Tymecka, D., et al. 2018. Eur J Med Chem. 158: 453-462. PMID: 30241012
- Facile Solid-Phase Synthesis of Well-Defined Defect Lysine Dendrimers. | Liao, Y., et al. 2022. ACS Omega. 7: 22896-22905. PMID: 35811872
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Boc-Lys(Fmoc)-OH, 5 g | sc-234169 | 5 g | $134.00 |