Date published: 2026-2-7

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Boc-L-serine t-butyl ester (CAS 7738-22-9)

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Alternate Names:
Boc-L-serine tert-butyl ester; Boc-L-Ser-OtBu; (2S)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
Application:
Boc-L-serine t-butyl ester is a modified amino acid used for biochemical research
CAS Number:
7738-22-9
Purity:
≥95%
Molecular Weight:
261.31
Molecular Formula:
C12H23NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Boc-L-serine t-butyl ester is a protected amino acid derivative used in peptide synthesis research. The tert-butyl ester group protects the carboxyl end of the serine, while the Boc (tert-butoxycarbonyl) group provides protection for the amino functionality. This dual protection strategy is essential for the stepwise construction of peptides, allowing for the selective deprotection and coupling of amino acid residues. Researchers utilize Boc-L-serine t-butyl ester to study the synthesis of serine-containing peptides, investigating the stability and reactivity of the protected intermediates under various conditions. The compound is also used in solid-phase peptide synthesis (SPPS), where the acid-labile Boc group is advantageous due to its removal under mild acidic conditions, which do not affect the integrity of the peptide chain anchored to the solid support.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Boc-L-serine t-butyl ester, 250 mg

sc-293881
250 mg
$48.00

Boc-L-serine t-butyl ester, 1 g

sc-293881A
1 g
$126.00