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Boc-L-Lys(Z)-pNA (CAS 51078-31-0)

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Alternate Names:
Nα-Boc-Nε-Z-L-Lysine-4-Nitroanilide
Application:
Boc-L-Lys(Z)-pNA is a chromogenic substrate
CAS Number:
51078-31-0
Molecular Weight:
500.54
Molecular Formula:
C25H32N4O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Boc-L-Lys(Z)-pNA is an important compound used in biochemistry research, particularly in the study of enzymatic activity and kinetics. It serves as a chromogenic substrate for proteases, which allows for the monitoring of enzyme activity through the release of p-nitroaniline, a compound that can be quantitatively measured by its absorbance. This characteristic makes Boc-L-Lys(Z)-pNA valuable in enzymology assays where researchers seek to understand protease function or to screen for protease inhibitors. The specificity of this substrate towards certain enzymes also aids in characterizing enzyme selectivity and preference for particular amino acid sequences. Additionally, Boc-L-Lys(Z)-pNA is utilized in the synthesis of peptides, where protecting groups such as Boc (t-butoxycarbonyl) and Z (benzyloxycarbonyl) are employed to regulate the reactivity of amino groups during peptide chain elongation.


Boc-L-Lys(Z)-pNA (CAS 51078-31-0) References

  1. New methods and reagents in organic synthesis. 69. A new synthesis of alpha-amino acid and peptide amides of aromatic amines using a modified Curtius reaction with diphenyl phosphorazidate.  |  Shioiri, T., et al. 1987. Chem Pharm Bull (Tokyo). 35: 2698-704. PMID: 3677226

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Boc-L-Lys(Z)-pNA, 5 g

sc-293849
5 g
$149.00

Boc-L-Lys(Z)-pNA, 25 g

sc-293849A
25 g
$406.00