Boc-D-Ser-O-Bzl (CAS 141527-78-8)

Boc-D-Ser-O-Bzl, a derivative of the amino acid D-serine, has been a focal point in scientific research due to its pivotal role in peptide synthesis and chemical biology studies. Specifically, it serves as a crucial building block in the solid-phase synthesis of peptides, where it is employed as a protected amino acid to facilitate stepwise peptide chain elongation. In peptide synthesis, Boc-D-Ser-O-Bzl is utilized as a substrate for coupling reactions with other amino acids, enabling the precise assembly of peptide sequences with desired functionalities and structural motifs. The tert-butyloxycarbonyl (Boc) protecting group on the serine residue safeguards its amino functionality during peptide bond formation, ensuring selective coupling reactions and preventing unwanted side reactions. Moreover, Boc-D-Ser-O-Bzl has been instrumental in the development of novel peptide-based materials and biomolecules with tailored properties and functions. Researchers have leveraged its versatility in peptide chemistry to engineer peptides with diverse biological activities, such as enzyme inhibition, receptor binding, and antimicrobial properties. Furthermore, this compound has found application in chemical biology studies aimed at elucidating the structure-function relationships of peptides and proteins. By incorporating Boc-D-Ser-O-Bzl into peptide substrates or probes, scientists can investigate protein-ligand interactions, enzyme catalysis mechanisms, and cellular signaling pathways, thus advancing our understanding of biological processes at the molecular level.