Date published: 2026-4-30

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Boc-6-Ahx-OH (CAS 6404-29-1)

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Alternate Names:
N-t-Butyloxycarbonyl-6-amino-hexanoic acid
CAS Number:
6404-29-1
Purity:
≥98%
Molecular Weight:
231.29
Molecular Formula:
C11H21NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Boc-6-Ahx-OH is a lysine derivative where the amine group is protected by the tert-butoxycarbonyl (Boc) group. This white crystalline substance dissolves in water and many organic solvents. It is widely used in peptide synthesis because it is an amino acid that can be easily incorporated into peptide chains. The Boc group plays a protective role, preventing the amine group from undesired reactions. Yet, when needed, this protective group can be simply stripped away under gentle acidic conditions. Boc-6-Ahx-OH serves not only in crafting esters of 6-aminohexanoic acid, which act as antibacterial agents, but it also has reported inhibitory effects on enzymes like chymotrypsin, Factor VIIa, and plasmin, among others.


Boc-6-Ahx-OH (CAS 6404-29-1) References

  1. Magnetic nanoparticle-conjugated polymeric micelles for combined hyperthermia and chemotherapy.  |  Kim, HC., et al. 2015. Nanoscale. 7: 16470-80. PMID: 26395038
  2. Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes.  |  Poreba, M., et al. 2020. J Am Chem Soc. 142: 16704-16715. PMID: 32870676
  3. Simultaneously monitoring endogenous MAPK members in single living cells by multi-channel fluorescence correlation spectroscopy.  |  Deng, L., et al. 2021. Analyst. 146: 2581-2590. PMID: 33899064
  4. Environmental effects of chitosan as an immobilization medium for electrochemically active small molecules  |  Marianne E. Burnett, Nelli Bodiford, Meghen E. Goulet, Jeffery L. Coffer & Kayla N. Green. 2019. Journal of Coordination Chemistry. 72: 2160-2176.
  5. Towards simultaneous quantification of protease inhibitors and inflammatory biomarkers in serum for people living with HIV  |  Pengyi Wang,a Charles S. Venuto, b Raymond Chac and Benjamin L. Miller *ad . 2020. Anal. Methods,. 12: 1882-1888.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Boc-6-Ahx-OH, 5 g

sc-293692
5 g
$65.00

Boc-6-Ahx-OH, 25 g

sc-293692A
25 g
$211.00