BMS-708163 CAS: 1146699-66-2
MF: C20H17ClF4N4O4S
MW: 520.88
A γ-secretase inhibitor.

BMS-708163 (CAS 1146699-66-2)

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Alternate Names: Avagacestat
Application: BMS-708163 is a γ-secretase inhibitor
CAS Number: 1146699-66-2
Purity: ≥98%
Molecular Weight: 520.88
Molecular Formula: C20H17ClF4N4O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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BMS-708163 is an inhibitor of the γ-secretase complex which is composed of four proteins: presenilin, nicastrin, APH-1 and PEN-2. BMS-708163 is shown to block Aβ40 and Aβ42 activity.

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Solubility :
≥104 mg/mL in DMSO <1 mg/mL in Water ≥8 mg/mL in Ethanol
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
C1=CC(=CC=C1S(=O)(=O)N(CC2=C(C=C(C=C2)C3=NOC=N3)F)C(CCC(F)(F)F)C(=O)N)Cl

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BMS-708163 (CAS 1146699-66-2)  Product Citations

See how others have used BMS-708163 (CAS 1146699-66-2). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25561332  Xie, M. et al. 2015. J. Cell. Biochem. 116: 1019-27.

Citations 1 to 1 of 1 total
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