BMS-708163 CAS: 1146699-66-2
MF: C20H17ClF4N4O4S
MW: 520.88
A γ-secretase inhibitor.

BMS-708163 (CAS 1146699-66-2)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 110ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: Avagacestat
Application: A γ-secretase inhibitor
CAS Number: 1146699-66-2
Purity: ≥98%
Molecular Weight: 520.88
Molecular Formula: C20H17ClF4N4O4S
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

BMS-708163 is an inhibitor of the γ-secretase complex which is composed of four proteins: presenilin, nicastrin, APH-1 and PEN-2. BMS-708163 is shown to block Aβ40 and Aβ42 activity.

Appearance :
Powder
Solubility :
≥104 mg/mL in DMSO <1 mg/mL in Water ≥8 mg/mL in Ethanol
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
46883536
SMILES :
C1=CC(=CC=C1S(=O)(=O)N(CC2=C(C=C(C=C2)C3=NOC=N3)F)C(CCC(F)(F)F)C(=O)N)Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

BMS-708163  Product Citations

See how others have used BMS-708163. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25561332  Xie, M. et al. 2015. J. Cell. Biochem. 116: 1019-27.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 121ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.