BMP-5 Antibody (L-16): sc-73747
- BMP-5 Antibody (L-16) is a mouse monoclonal IgG2a, cited in 1 publications, provided at 100 µg/ml
- raised against full length recombinant BMP-5 of human origin
- recommended for detection of BMP-5 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BMP-5 Antibody (L-16). This work is in progress.
BMP-5 Antibody (L-16) is a mouse monoclonal IgG2a antibody that detects BMP-5 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). BMP-5 is a crucial member of the bone morphogenetic protein (BMP) family, which is part of the transforming growth factor-beta (TGFβ) superfamily, and plays a significant role in the regulation of bone and cartilage development. BMP-5 is primarily located in the extracellular matrix, where BMP-5 is secreted and interacts with specific receptors on the cell surface, initiating signaling pathways that lead to cellular differentiation and tissue formation. This localization is vital as BMP-5 exerts effects on neighboring cells, influencing processes such as osteogenesis and chondrogenesis, which are essential for skeletal development and repair. Furthermore, BMP-5 has been shown to interact with other BMPs and signaling molecules, enhancing functional repertoire in developmental biology and tissue regeneration. Anti-BMP-5 antibody (L-16) is an invaluable tool for researchers studying these critical biological processes and the underlying mechanisms of bone and cartilage formation.
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BMP-5 Antibody (L-16) References:
- Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons. | Beck, HN., et al. 2001. BMC Neurosci. 2: 12. PMID: 11580864
- BMP-5 expression increases during chondrocyte differentiation in vivo and in vitro and promotes proliferation and cartilage matrix synthesis in primary chondrocyte cultures. | Mailhot, G., et al. 2008. J Cell Physiol. 214: 56-64. PMID: 17541940
- The role of bone morphogenetic protein-5 (BMP-5) in human nephrosclerosis. | Bramlage, CP., et al. 2011. J Nephrol. 24: 647-55. PMID: 21319131
- Epithelial-to-mesenchymal transition induced by TGF-β1 is mediated by Blimp-1-dependent repression of BMP-5. | Romagnoli, M., et al. 2012. Cancer Res. 72: 6268-78. PMID: 23054396
- Bone morphogenetic proteins in the bovine oviduct: differential expression of BMP-5 in the isthmus during the estrous cycle. | García, EV., et al. 2014. Theriogenology. 81: 1032-41. PMID: 24582268
- Bone morphogenetic proteins. | Wozney, JM. 1989. Prog Growth Factor Res. 1: 267-80. PMID: 2491264
- Bone morphogenetic protein-5, a key molecule that mediates differentiation in MC3T3E1 osteoblast cell line. | Vijayan, V., et al. 2017. Biofactors. 43: 558-566. PMID: 28497879
- High serum levels of BMP-2 correlate with BMP-4 and BMP-5 levels and induce reduced neuronal phenotype in patients with relapsing-remitting multiple sclerosis. | Penn, M., et al. 2017. J Neuroimmunol. 310: 120-128. PMID: 28778435
- Expression of Bone Morphogenetic Proteins in Multiple Sclerosis Lesions. | Costa, C., et al. 2019. Am J Pathol. 189: 665-676. PMID: 30553833
- Prenatal origin of brachymesophalangia-5. | Garn, SM., et al. 1976. Am J Phys Anthropol. 44: 413-6. PMID: 937520
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BMP-5 Antibody (L-16) | sc-73747 | 100 µg/ml | $322.00 |