BM-531 (CAS 284464-46-6)

BM-531 is a potent synthetic compound recognized for its dual antagonistic action on serotonin (5-HT2) and thromboxane A2/prostaglandin H2 (TP) receptors. Its structure enables it to serve as a valuable tool for investigating the signaling pathways mediated by these receptor systems. In research applications, BM-531 has been widely utilized to understand the physiological roles of serotonin and thromboxane receptors, particularly in the context of vascular function. By blocking 5-HT2 receptors, it sheds light on serotonin′s impact on smooth muscle contraction and platelet aggregation. Similarly, BM-531′s TP receptor antagonism provides crucial data on the involvement of thromboxane in vasoconstriction and thrombosis. It aids researchers in deciphering the specific interactions between serotonin and thromboxane pathways, which often converge in cardiovascular and neurological functions. Scientists use BM-531 to discern the distinct roles and interplay of these signaling pathways under various physiological and pathological conditions. Furthermore, it serves as a reference molecule in comparative studies that explore other dual-action antagonists, offering insight into structure-activity relationships. As such, BM-531 is instrumental in elucidating receptor function, helping researchers map out receptor distribution and functional effects within complex biological systems.