BM 15766 sulfate (CAS 86621-94-5)
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BM 15766 sulfate, recognized as an inhibitor of the enzyme DHCR7, is a compound of particular interest in biochemical research focusing on the cholesterol biosynthesis pathway. By inhibiting DHCR7, an enzyme critical to the final steps of cholesterol synthesis, BM 15766 sulfate serves as a tool for scientists to dissect and better understand cholesterol metabolism and its associated cellular processes. This compound′s activity is leveraged in studies exploring the regulation of cholesterol levels within cells, and its role in cell membrane structure and function. Additionally, in molecular biology, it is used to artificially induce conditions that mimic genetic disruptions of cholesterol synthesis, providing insights into the cellular consequences of such disruptions.
BM 15766 sulfate (CAS 86621-94-5) References
- The anti-tubercular activity of simvastatin is mediated by cholesterol-driven autophagy via the AMPK-mTORC1-TFEB axis. | Bruiners, N., et al. 2020. J Lipid Res. 61: 1617-1628. PMID: 32848049
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BM 15766 sulfate, 1 mg | sc-210953 | 1 mg | $225.00 | |||
BM 15766 sulfate, 5 mg | sc-210953A | 5 mg | $849.00 |