Blood Group N antigen Antibody (DRF-8): sc-52374

Blood Group N antigen Antibody (DRF-8) is a mouse monoclonal IgG2b antibody that detects Blood Group N antigen protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Blood Group N antigen (DRF-8) antibody is available in both non-conjugated and various conjugated forms, including fluorescein isothiocyanate (FITC), providing versatility for different experimental needs. Blood Group N antigen (DRF-8) monoclonal antibody recognizes a crucial component of the blood group system, characterized by its role in cell recognition and signaling, which is vital for immune response and cellular interactions. Blood Group N antigen protein is primarily located on the surface of erythrocytes and certain epithelial cells, where Blood Group N antigen (DRF-8) antibody contributes to the structural integrity of the cell membrane and plays a significant role in determining blood compatibility during transfusions. Blood Group N antigen protein is part of a larger family of blood group antigens that can undergo changes during malignant transformation, making Blood Group N antigen (DRF-8) monoclonal antibody an important marker in cancer research. Understanding the expression and modulation of Blood Group N antigen protein can provide insights into tumor biology and the development of targeted therapies.

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Blood Group N antigen Antibody (DRF-8) References:

1. Blood group N antigen precursor glycoproteins and N antigen precursor glycoproteins with Thomsen-Friedenreich (T) activity from human liver metastatic carcinomas.  |  Otsuka, K., et al. 1991. Int J Biochem. 23: 569-78. PMID: 1648519
2. Two monoclonal antibodies recognizing different epitopes of blood group N antigen.  |  Waśniowska, K., et al. 1988. Arch Immunol Ther Exp (Warsz). 36: 623-32. PMID: 2478103
3. Radioassays of blood group M, N and T (Thomsen-Friedenreich) antigens.  |  King, MJ. and Holburn, AM. 1979. Immunology. 38: 129-36. PMID: 511213
4. Biochemistry and Genetics of the ABO, Lewis, and P blood group systems.  |  Watkins, WM. 1980. Adv Hum Genet. 10: 1-136, 379-85. PMID: 6156588
5. Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens.  |  Borén, T., et al. 1993. Science. 262: 1892-5. PMID: 8018146
6. Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity.  |  Appelmelk, BJ., et al. 1996. Infect Immun. 64: 2031-40. PMID: 8675304
7. Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging.  |  Ilver, D., et al. 1998. Science. 279: 373-7. PMID: 9430586

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Blood Group N antigen Antibody (DRF-8) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Blood Group N antigen Antibody (DRF-8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Blood Group N antigen Antibody (DRF-8) Specifications

Alternate Product Name: Blood Group N antigen

Product Clone Name: DRF-8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b

Amino Acids:

Epitope Target: Blood Group N antigen

Epitope Species: human

Product Reactivity/Detection: Blood Group N antigen

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 100 µg IgG_2b in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Blood Group N antigen Antibody (DRF-8): FITC: Fluoroscein