Blood Group Lewis b Antibody (T218): sc-59470

Blood Group Lewis b Antibody (T218) is a mouse monoclonal IgM kappa light chain antibody that detects Blood Group Lewis b (Type 1 chain) of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Blood Group Lewis b (T218) antibody is available in a non-conjugated form, allowing for versatile applications in various experimental settings. Blood Group Lewis b antigen plays a crucial role in cell-cell interactions and is primarily located on the surface of cells, where Blood Group Lewis b contributes to the regulation of immune responses and cellular adhesion. This carbohydrate determinant is essential for the proper functioning of selectins, which are adhesion molecules that mediate the rolling of leukocytes along the vascular endothelium during inflammation. Blood Group Lewis b on cell surfaces influences the recruitment of immune cells to sites of injury or infection, thereby facilitating effective immune responses. Additionally, Blood Group Lewis b expression is vital for the development of hematopoietic lineages, as Blood Group Lewis b helps define the surface carbohydrate phenotype necessary for cell trafficking and adhesion. Anti-Blood Group Lewis b antibody (T218) can provide valuable insights into the mechanisms of immune cell behavior and the role of glycosylation in health and disease.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Blood Group Lewis b Antibody (T218) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-Blood Group Lewis b Antibody (T218) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Blood Group Lewis b Antibody (T218) Specifications

Alternate Product Name: Blood Group Lewis b

Product Clone Name: T218

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids:

Epitope Target: Blood Group Lewis b

Epitope Species: human

Product Reactivity/Detection: Blood Group Lewis b (Type 1 chain)

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for Blood Group Lewis b Antibody (T218): N/A

The preferred Blood Group Lewis b antibody is Blood Group Lewis b Antibody (2-25LE): sc-51513.