Date published: 2026-5-22

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Blood group B trisaccharide (CAS 49777-14-2)

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Alternate Names:
Gal-α-1,3(Fuc-α-1,2)Gal
Application:
Blood group B trisaccharide is a polysaccharide
CAS Number:
49777-14-2
Purity:
≥95%
Molecular Weight:
488.44
Molecular Formula:
C18H32O15
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The Blood Group B trisaccharide, a carbohydrate consisting of three sugar units, has garnered significant attention in scientific research due to its implications in blood group antigen recognition and carbohydrate chemistry. One specific mechanism of action involves its interaction with blood group antigens present on the surface of red blood cells and various tissues. Researchers have utilized the Blood Group B trisaccharide as a model system to study carbohydrate-protein interactions, particularly those involved in blood group antigen recognition by lectins and antibodies. Understanding these interactions at the molecular level provides insights into immune responses, transplantation compatibility, and disease susceptibility. Moreover, the synthesis and structural characterization of the Blood Group B trisaccharide have contributed to the development of novel glycoconjugates, glycopeptides, and glycomimetics with potential applications in drug delivery, vaccine development, and diagnostic tools. Additionally, research efforts have focused on the enzymatic synthesis of Blood Group B trisaccharide analogs and the design of glycosylation strategies for the site-selective modification of biomolecules. Overall, the Blood Group B trisaccharide serves as a valuable tool in carbohydrate chemistry and glycobiology research, facilitating the exploration of carbohydrate-mediated biological processes.


Blood group B trisaccharide (CAS 49777-14-2) References

  1. alpha-Gal epitopes in animal tissue glycoproteins and glycolipids.  |  Rydberg, L., et al. 1999. Subcell Biochem. 32: 107-25. PMID: 10391993
  2. Enzymatic synthesis of blood group A and B trisaccharide analogues.  |  Seto, NO., et al. 2000. Carbohydr Res. 324: 161-9. PMID: 10724530
  3. Purification, characterization, and cDNA cloning of alpha-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera.  |  Kakiuchi, M., et al. 2002. Glycobiology. 12: 85-94. PMID: 11886841
  4. Characterization of the recognition of blood group B trisaccharide derivatives by the lectin from Marasmius oreades using frontal affinity chromatography-mass spectrometry.  |  Rempel, BP., et al. 2002. Glycoconj J. 19: 175-80. PMID: 12815228
  5. Enzymatic transfer of a preassembled trisaccharide antigen to cell surfaces using a fucosyltransferase.  |  Srivastava, G., et al. 1992. J Biol Chem. 267: 22356-61. PMID: 1429589
  6. Landing preference of Aedes albopictus (Diptera: Culicidae) on human skin among ABO blood groups, secretors or nonsecretors, and ABH antigens.  |  Shirai, Y., et al. 2004. J Med Entomol. 41: 796-9. PMID: 15311477
  7. Crystallization and preliminary X-ray crystallographic studies of a lectin from the mushroom Marasmius oreades.  |  Grahn, E., et al. 2004. Acta Crystallogr D Biol Crystallogr. 60: 2038-9. PMID: 15502320
  8. Structural characterization of a lectin from the mushroom Marasmius oreades in complex with the blood group B trisaccharide and calcium.  |  Grahn, EM., et al. 2009. J Mol Biol. 390: 457-66. PMID: 19426740
  9. Structural basis for langerin recognition of diverse pathogen and mammalian glycans through a single binding site.  |  Feinberg, H., et al. 2011. J Mol Biol. 405: 1027-39. PMID: 21112338
  10. Anti-glycan IgM repertoires in newborn human cord blood.  |  Xia, L. and Gildersleeve, JC. 2019. PLoS One. 14: e0218575. PMID: 31365539

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Blood group B trisaccharide, 1 mg

sc-257108
1 mg
$589.00