Molecular structure of Bitolterol Mesylate, CAS Number: 30392-41-7
Bitolterol Mesylate (CAS 30392-41-7)
Alternate Names:
4-Methyl-benzoic Acid 1,1′-[4-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,2-phenylene] Ester Methanesulfonate
CAS Number:
30392-41-7
Molecular Weight:
557.66
Molecular Formula:
C29H35NO8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Bitolterol Mesylate, the mesylate salt derived from bitolterol, belongs to the class of diester sympathomimetic amines. Bitolterol undergoes hydrolysis by esterases, giving rise to its active metabolite colterol (N-t-butylarterenol). Selectively binding to and activating beta-2 adrenergic receptors. Colterol initiates the stimulation of adenyl cyclase, an enzyme responsible for converting adenosine triphosphate (ATP) to cyclic-3′,5′-adenosine monophosphate (cAMP). This leads to the relaxation of bronchial smooth muscle, resulting in bronchodilation.
Bitolterol Mesylate (CAS 30392-41-7) References
- Retrospective study of bitolterol mesylate in the treatment of conditions associated with reversible bronchospasm. | Messina, MS. 1995. Adv Ther. 12: 157-63. PMID: 10155050
- The effect of column age on system suitability parameters for an HPLC assay of bitolterol mesylate aerosols. | Wilson, TD. and Fogarty, DF. 1988. J Chromatogr Sci. 26: 60-6. PMID: 3350902
- Bitolterol mesylate: a beta-adrenergic agent. Chemistry, pharmacokinetics, pharmacodynamics, adverse effects and clinical efficacy in asthma. | Walker, SB., et al. 1985. Pharmacotherapy. 5: 127-37. PMID: 3895171
- Comparison of bronchodilator responses with bitolterol mesylate solution with the use of two different nebulizer systems in asthma. | Kemp, JP., et al. 1986. J Allergy Clin Immunol. 77: 509-15. PMID: 3950254
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bitolterol Mesylate, 25 mg | sc-503852 | 25 mg | $380.00 |