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Bisphenol A bis(2,3-dihydroxypropyl) ether (CAS 5581-32-8)

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Alternate Names:
2,2-Bis[4-(2,3-dihydroxypropoxy)phenyl]propane
Application:
Bisphenol A bis(2,3-dihydroxypropyl) ether is a standard for the determination of toxic monomers
CAS Number:
5581-32-8
Purity:
≥97%
Molecular Weight:
376.44
Molecular Formula:
C21H28O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bisphenol A bis(2,3-dihydroxypropyl) ether is a standard for the determination of toxic monomers released from polymers of the inner coating of cans. Bisphenol A bis(2,3-dihydroxypropyl) ether, a polymeric compound, has been widely employed in the manufacturing of polymers, plastics, and various materials. It serves as a stabilizer during polymer production, believed to achieve this by establishing robust chemical bonds with other molecules. This bonding mechanism effectively safeguards the polymer, preventing its degradation and maintaining its desired physical and chemical attributes.


Bisphenol A bis(2,3-dihydroxypropyl) ether (CAS 5581-32-8) References

  1. Aromatic dental monomers affect the activity of cholesterol esterase.  |  Smith, RE., et al. 2001. Biochim Biophys Acta. 1550: 100-6. PMID: 11738092
  2. In vitro assay of hydrolysis and chlorohydroxy derivatives of bisphenol A diglycidyl ether for estrogenic activity.  |  Nakazawa, H., et al. 2002. Food Chem Toxicol. 40: 1827-32. PMID: 12419697
  3. Determination of bisphenol A diglycidyl ether and its hydrolysis and chlorohydroxy derivatives by liquid chromatography-mass spectrometry.  |  Sendón García, R. and Paseiro Losada, P. 2004. J Chromatogr A. 1032: 37-43. PMID: 15065774
  4. Bisphenol A bis(2,3-dihydroxypropyl) ether (BADGE.2H2O) induces orphan nuclear receptor Nur77 gene expression and increases steroidogenesis in mouse testicular Leydig cells.  |  Ahn, SW., et al. 2008. Mol Cells. 26: 74-80. PMID: 18525235
  5. Excretion of dental resin monomers and metabolic intermediates via urine in guinea pigs.  |  Seiss, M., et al. 2009. Dent Mater. 25: 481-5. PMID: 19041128
  6. Fast liquid chromatography-tandem mass spectrometry for the analysis of bisphenol A-diglycidyl ether, bisphenol F-diglycidyl ether and their derivatives in canned food and beverages.  |  Gallart-Ayala, H., et al. 2011. J Chromatogr A. 1218: 1603-10. PMID: 21333297
  7. Effects of bisphenol A on the expression of cytochrome P450 aromatase (CYP19) in human fetal osteoblastic and granulosa cell-like cell lines.  |  Watanabe, M., et al. 2012. Toxicol Lett. 210: 95-9. PMID: 22327052
  8. Occurrence and human exposure of p-hydroxybenzoic acid esters (parabens), bisphenol A diglycidyl ether (BADGE), and their hydrolysis products in indoor dust from the United States and three East Asian countries.  |  Wang, L., et al. 2012. Environ Sci Technol. 46: 11584-93. PMID: 23025715
  9. A multi-class bioanalytical methodology for the determination of bisphenol A diglycidyl ethers, p-hydroxybenzoic acid esters, benzophenone-type ultraviolet filters, triclosan, and triclocarban in human urine by liquid chromatography-tandem mass spectrometry.  |  Asimakopoulos, AG., et al. 2014. J Chromatogr A. 1324: 141-8. PMID: 24315674
  10. Stabilities of bisphenol A diglycidyl ether, bisphenol F diglycidyl ether, and their derivatives under controlled conditions analyzed using liquid chromatography coupled with tandem mass spectrometry.  |  Szczepańska, N., et al. 2019. Anal Bioanal Chem. 411: 6387-6398. PMID: 31321469
  11. Measured concentrations of consumer product chemicals in California house dust: Implications for sources, exposure, and toxicity potential.  |  Shin, HM., et al. 2020. Indoor Air. 30: 60-75. PMID: 31587372
  12. Bisphenol A as degradation product of monomers used in resin-based dental materials.  |  De Nys, S., et al. 2021. Dent Mater. 37: 1020-1029. PMID: 33896600
  13. Urinary biomonitoring of occupational exposures to Bisphenol A Diglycidyl Ether (BADGE) - based epoxy resins among construction painters in metal structure coating.  |  Bello, A., et al. 2021. Environ Int. 156: 106632. PMID: 34020298

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bisphenol A bis(2,3-dihydroxypropyl) ether, 50 mg

sc-252492
50 mg
$153.00

Bisphenol A bis(2,3-dihydroxypropyl) ether, 500 mg

sc-252492A
500 mg
$306.00