Date published: 2026-2-19

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Bisoprolol-d5

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Application:
Bisoprolol-d5 is A selective β-adrenergic blocker
Molecular Weight:
330.47
Molecular Formula:
C18H26D5NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bisoprolol-d5 is a deuterated variant of bisoprolol, specifically designed for use in scientific research, particularly in the field of pharmacokinetics and metabolic studies. The incorporation of deuterium atoms in place of hydrogen allows for a detailed tracing and understanding of bisoprolol′s metabolic pathways without altering its biochemical behavior. This unique characteristic makes bisoprolol-d5 an invaluable tool in the precise measurement of bisoprolol′s absorption, distribution, metabolism, and excretion (ADME) properties in research applications. Its use facilitates the exploration of bisoprolol′s mechanism of action at a molecular level, enabling scientists to elucidate the intricacies of its interactions within biological systems. By providing a stable isotopic label, bisoprolol-d5 allows for the distinction between endogenous molecules and the compound of interest in complex biological matrices, enhancing the accuracy of analytical methods such as mass spectrometry. This enhanced understanding contributes significantly to the broader field of research by offering insights into the molecular dynamics and pharmacological behavior of bisoprolol.


Bisoprolol-d5 References

  1. Online and splitless NanoLC × CapillaryLC with quadrupole/time-of-flight mass spectrometric detection for comprehensive screening analysis of complex samples.  |  Haun, J., et al. 2013. Anal Chem. 85: 10083-90. PMID: 24063754
  2. Liquid chromatography-tandem mass spectrometry method for simultaneous quantification of bisoprolol, ramiprilat, propranolol and midazolam in rat dried blood spots.  |  Cvan Trobec, K., et al. 2014. J Chromatogr B Analyt Technol Biomed Life Sci. 958: 29-35. PMID: 24686237
  3. Occurrence of cardiovascular drugs in the sewage-impacted Vistula River and in tap water in the Warsaw region (Poland).  |  Giebułtowicz, J., et al. 2016. Environ Sci Pollut Res Int. 23: 24337-24349. PMID: 27655616
  4. Quantification of Bisoprolol and Metoprolol in Simultaneous Human Serum and Cerebrospinal Fluid Samples.  |  Sigaroudi, A., et al. 2018. Pharmacology. 101: 29-34. PMID: 28930747
  5. Quantification of 21 antihypertensive drugs in serum using UHPLC-MS/MS.  |  Gundersen, POM., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1089: 84-93. PMID: 29783197
  6. Quantification of Hydrochlorothiazide and Ramipril/Ramiprilate in Blood Serum and Cerebrospinal Fluid: A Pharmacokinetic Assessment of Central Nervous System Adverse Effects.  |  Sigaroudi, A., et al. 2018. Pharmacology. 102: 133-137. PMID: 29982257
  7. The assessment of environmental risk related to the occurrence of pharmaceuticals in bottom sediments of the Odra River estuary (SW Baltic Sea).  |  Kucharski, D., et al. 2022. Sci Total Environ. 828: 154446. PMID: 35283119

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bisoprolol-d5, 1 mg

sc-217772
1 mg
$388.00