Molecular structure of BIS-Tris Propane, CAS Number: 64431-96-5
BIS-Tris Propane (CAS 64431-96-5)
Alternate Names:
1,3-bis[tris(Hydroxymethyl)methylamino]propane
Application:
BIS-Tris Propane is a buffer that is useful in the pH 6.3-9.5 range
CAS Number:
64431-96-5
Purity:
≥99%
Molecular Weight:
282.4
Molecular Formula:
C11H26N2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
BIS-Tris Propane is a buffer that is useful in the pH 6.3 - 9.5 range. This wide buffering range is due to its two pKa values, 6.8 (pKa1) and 9.0 (pKa2), being so close. Because of the wide buffering range, particularly down to pH 6 - 7, this buffer has been used to enhance the stability or activity of restriction enzymes, compared to Tris buffer (which is a poor buffer below pH 7.5 and has a comparatively large change in pKa with temperature).
BIS-Tris Propane (CAS 64431-96-5) References
- Phosphodiester hydrolysis by lanthanide complexes of bis-tris propane. | Gómez-Tagle, P. and Yatsimirsky, AK. 2001. Inorg Chem. 40: 3786-96. PMID: 11442378
- Aggregation and other intermolecular interactions of biological buffers observed by capillary electrophoresis and UV photometry. | Vespalec, R., et al. 2004. J Chromatogr A. 1051: 75-84. PMID: 15532558
- Use of ionic and zwitterionic (Tris/BisTris and HEPES) buffers in studies on hemoglobin function. | Weber, RE. 1992. J Appl Physiol (1985). 72: 1611-5. PMID: 1592755
- DNA polymerase fidelity and the polymerase chain reaction. | Eckert, KA. and Kunkel, TA. 1991. PCR Methods Appl. 1: 17-24. PMID: 1842916
- Bis-tris propane as a new polydentate linker in the synthesis of iron(III) and manganese(II/III) complexes. | Ferguson, A., et al. 2008. Inorg Chem. 47: 9742-4. PMID: 18834191
- Sequence-dependent gelation kinetics of β-hairpin peptide hydrogels. | Larsen, TH., et al. 2009. Macromolecules. 42: 8443-8450. PMID: 20161466
- Bis-tris propane as a new multidentate ligand for nickel- and cobalt-based spin clusters. | Ferguson, A., et al. 2011. Dalton Trans. 40: 334-6. PMID: 21109891
- Polyamines Counteract Carbonate-Driven Proteasome Stalling in Alkaline Conditions. | Kudriaeva, AA., et al. 2020. Biomolecules. 10: PMID: 33255475
- Photogeneration and reactivity of flavin anionic semiquinone in a bifurcating electron transfer flavoprotein. | Duan, HD., et al. 2021. Biochim Biophys Acta Bioenerg. 1862: 148415. PMID: 33727071
- Protein association on multimodal chromatography media. | Muca, R. and Antos, D. 2023. J Chromatogr A. 1691: 463827. PMID: 36731331
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BIS-Tris Propane, 100 g | sc-216089 | 100 g | $175.00 |