Date published: 2026-5-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

BIS-TRIS hydrochloride (CAS 124763-51-5)

0.0(0)
Write a reviewAsk a question

Alternate Names:
2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol; 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol; Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane
CAS Number:
124763-51-5
Molecular Weight:
245.7
Molecular Formula:
C8H20ClNO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

BIS-TRIS hydrochloride, serves as a chemical compound widely employed in various scientific research endeavors. It manifests as a white, crystalline solid with a molecular weight of 227.64 g/mol. Derived from 2-amino-2-methyl-1,3-propanediol—an essential buffer in the field of biochemistry and molecular biology—BIS-TRIS hydrochloride possesses zwitterionic properties, displaying both positive and negative charges. This characteristic renders it invaluable for numerous laboratory experiments. BIS-TRIS hydrochloride finds extensive usage in scientific research, encompassing a wide range of applications. Particularly, it serves as a employed buffer in biochemistry and molecular biology experiments. Moreover, BIS-TRIS hydrochloride acts as a valuable nitrogen and carbon source in cell culture experiments. Additionally, it fulfills a role as an ion-pairing agent in chromatography experiments. Thanks to its zwitterionic nature, BIS-TRIS hydrochloride interacts with the positive and negative charges of the molecules under separation, facilitating their more effective separation.


BIS-TRIS hydrochloride (CAS 124763-51-5) References

  1. Phos-tag SDS-PAGE systems for phosphorylation profiling of proteins with a wide range of molecular masses under neutral pH conditions.  |  Kinoshita, E., et al. 2012. Proteomics. 12: 192-202. PMID: 22121028
  2. Electrogenerated chemiluminescence of tris(2,2' bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte.  |  Kebede, N., et al. 2015. Analyst. 140: 7142-5. PMID: 26347905
  3. Purification and characterization of diamine oxidase from porcine kidney and intestine.  |  Schwelberger, HG. and Bodner, E. 1997. Biochim Biophys Acta. 1340: 152-64. PMID: 9217025

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

BIS-TRIS hydrochloride, 100 g

sc-257157
100 g
$204.00

BIS-TRIS hydrochloride, 500 g

sc-257157A
500 g
$587.00