Date published: 2026-5-31

1-800-457-3801

SCBT Portrait Logo
Seach Input

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride (CAS 68641-49-6)

0.0(0)
Write a reviewAsk a question

Alternate Names:
BOP-Cl
CAS Number:
68641-49-6
Purity:
≥97%
Molecular Weight:
254.56
Molecular Formula:
C6H8ClN2O5P
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride functions as a phosphorus-based reagent in chemical synthesis. It acts as a phosphorylating agent, facilitating the introduction of phosphinic acid functionalities into organic molecules. Bis(2-Oxo-3-Oxazolidinyl)Phosphinic Chloride′s mechanism of action involves the formation of phosphinic acid derivatives through the reaction with nucleophilic groups, such as hydroxyl or amino groups, in the target molecules. This reaction results in the formation of phosphinic acid esters, which can be further manipulated in various synthesis pathways. Bis(2-oxo-3-oxazolidinyl)phosphinic chloride′s role in chemical synthesis involves the modification of organic molecules to introduce phosphinic acid moieties, enabling the creation of diverse chemical structures for research and development purposes. Its mechanism of action at the molecular level involves the formation of covalent bonds with nucleophilic groups, leading to the incorporation of phosphinic acid functionalities into the target molecules.


Bis(2-oxo-3-oxazolidinyl)phosphinic chloride (CAS 68641-49-6) References

  1. Frogolide - An Unprecedented Sesquiterpene Macrolactone from Scent Glands of African Frogs.  |  Menke, M., et al. 2018. European J Org Chem. 2018: 2651-2656. PMID: 30078994
  2. Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis.  |  Siebert, DCB., et al. 2019. Beilstein J Org Chem. 15: 2922-2929. PMID: 31839838
  3. Methods for Hydroxamic Acid Synthesis.  |  Alam, MA. 2019. Curr Org Chem. 23: 978-993. PMID: 32565717
  4. Synthesis and Evaluation of Antimycobacterial and Antiplasmodial Activities of Hirsutellide A and Its Analogues.  |  Sahile, HA., et al. 2020. ACS Omega. 5: 14451-14460. PMID: 32596583
  5. Total Synthesis of Endolides A and B.  |  Liu, L., et al. 2019. Synlett. 30: 2279-2284. PMID: 34163101
  6. Diversity-Oriented Synthesis: Amino Acetophenones as Building Blocks for the Synthesis of Natural Product Analogs.  |  Eymery, M., et al. 2021. Pharmaceuticals (Basel). 14: PMID: 34832909
  7. Solid-Phase Synthesis of Boranophosphate/Phosphorothioate/Phosphate Chimeric Oligonucleotides and Their Potential as Antisense Oligonucleotides.  |  Takahashi, Y., et al. 2022. J Org Chem. 87: 3895-3909. PMID: 34908418
  8. Ames Salmonella/mammalian-microsome testing of peptides and peptide synthesis reagents.  |  Allen, JS. and Panfili, J. 1986. Mutat Res. 170: 23-9. PMID: 3515165
  9. Carbodiimide-Mediated Beckmann Rearrangement of Oxyma-B as a Side Reaction in Peptide Synthesis.  |  Orlandin, A., et al. 2022. Molecules. 27: PMID: 35807480
  10. Synthesis of tryptophan-dehydrobutyrine diketopiperazine and biological activity of hangtaimycin and its co-metabolites.  |  Xu, H., et al. 2022. Beilstein J Org Chem. 18: 1159-1165. PMID: 36128431
  11. Phase Regulation and Defect Passivation Enabled by Phosphoryl Chloride Molecules for Efficient Quasi-2D Perovskite Light-Emitting Diodes.  |  Li, M., et al. 2023. Nanomicro Lett. 15: 119. PMID: 37127730
  12. Analogues of the cytostatic and antimitogenic agents chlamydocin and HC-toxin: synthesis and biological activity of chloromethyl ketone and diazomethyl ketone functionalized cyclic tetrapeptides.  |  Shute, RE., et al. 1987. J Med Chem. 30: 71-8. PMID: 3806605
  13. Nonionic surfactants regioselective synthesis of fatty acid esters of alpha- and beta-glucopyranose.  |  De Luca, D., et al. 1997. Lipids. 32: 559-63. PMID: 9168463

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, 5 g

sc-252443
5 g
$50.00