Molecular structure of Bis(2-chloroethoxy)methane, CAS Number: 111-91-1
Bis(2-chloroethoxy)methane (CAS 111-91-1)
Alternate Names:
Dichloroethyl Formal; Dichloroethylformal
CAS Number:
111-91-1
Purity:
≥97%
Molecular Weight:
173.04
Molecular Formula:
C5H10Cl2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Bis(2-chloroethoxy)methane is thought to exert its effects by functioning as an alkylating agent. This property enables it to interact with nucleophilic groups found in biological molecules, including proteins and DNA, resulting in the formation of covalent bonds. Consequently, these interactions can induce alterations in the structure and functionality of the molecules, thereby influencing cellular processes in diverse ways.
Bis(2-chloroethoxy)methane (CAS 111-91-1) References
- Bis(2-chloroethoxy)methane-induced mitochondrial and myofibrillar damage: short-term time-course study. | Dunnick, J., et al. 2004. Toxicol Sci. 81: 243-52. PMID: 15201436
- Cardiac damage in rodents after exposure to bis(2-chloroethoxy)methane. | Dunnick, JK., et al. 2004. Toxicol Pathol. 32: 309-17. PMID: 15204972
- Environmental cardiology: getting to the heart of the matter. | Weinhold, B. 2004. Environ Health Perspect. 112: A880-7. PMID: 15531422
- Critical pathways in heart function: bis(2-chloroethoxy)methane-induced heart gene transcript change in F344 rats. | Dunnick, J., et al. 2006. Toxicol Pathol. 34: 348-56. PMID: 16844662
- Occult cardiotoxicity: subtoxic dosage of Bis(2-chloroethoxy)methane impairs cardiac response to simulated ischemic injury. | Golomb, E., et al. 2007. Toxicol Pathol. 35: 383-7. PMID: 17455086
- [14C]bis(2-chloroethoxy)methane: comparative absorption, distribution, metabolism and excretion in rats and mice. | Black, SR., et al. 2007. Xenobiotica. 37: 427-40. PMID: 17455114
- Surface catalyzed Fenton treatment of bis(2-chloroethyl) ether and bis(2-chloroethoxy) methane. | Mutuc, MD., et al. 2008. Chemosphere. 70: 1390-8. PMID: 18061235
- Bis(2-chloroethoxy)methane degradation by TiO2 photocatalysis: parameter and reaction pathway investigations. | Chen, CC., et al. 2009. J Hazard Mater. 172: 1021-32. PMID: 19720461
- The pivotal role of electron microscopic evaluation in investigation of the cardiotoxicity of bis(2-chloroethoxy)methane in rats and mice. | Nyska, A., et al. 2009. Toxicol Pathol. 37: 873-7. PMID: 19770349
- Toxicokinetics of bis(2-chloroethoxy)methane following intravenous administration and dermal application in male and female F344/N rats and B6C3F1 mice. | Waidyanatha, S., et al. 2011. Toxicol Lett. 205: 215-26. PMID: 21708233
- Toxicology and carcinogenesis studies of bis(2-chloroethoxy)methane (CAS No. 111-91-1) in F344/N rats and B6C3F1 mice (dermal studies). | ,. 2011. Natl Toxicol Program Tech Rep Ser. 1-203. PMID: 21921961
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bis(2-chloroethoxy)methane, 5 g | sc-326304 | 5 g | $205.00 |