Date published: 2026-4-30

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Bis-(1-chloro-2-propyl)phosphate (CAS 789440-10-4)

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Alternate Names:
1-Chloro-2-propanol Hydrogen Phosphate; BCPP
CAS Number:
789440-10-4
Molecular Weight:
251.04
Molecular Formula:
C6H13Cl2O4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bis-(1-chloro-2-propyl)phosphate is a chemical compound that has attention in environmental chemistry and toxicology research. Studies focus on its role as a flame retardant additive in various consumer products and the implications of its persistence and bioaccumulation in ecosystems. Research involving Bis-(1-chloro-2-propyl)phosphate often examines its environmental fate, including its degradation products, transport mechanisms in water and soil, and potential for accumulation in wildlife and human tissues. Additionally, the compound is studied for its chemical stability and its interaction with other components in flame retardant formulations. Investigations also delve into the development of analytical methods for the detection and quantification of Bis-(1-chloro-2-propyl)phosphate in environmental samples, contributing to the understanding of its distribution and potential impact on health and the environment.


Bis-(1-chloro-2-propyl)phosphate (CAS 789440-10-4) References

  1. Analysis of organophosphate flame retardant diester metabolites in human urine by liquid chromatography electrospray ionisation tandem mass spectrometry.  |  Van den Eede, N., et al. 2013. J Chromatogr A. 1303: 48-53. PMID: 23849782
  2. Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers.  |  Butt, CM., et al. 2014. Environ Sci Technol. 48: 10432-8. PMID: 25090580
  3. A high-throughput method for determination of metabolites of organophosphate flame retardants in urine by ultra performance liquid chromatography-high resolution mass spectrometry.  |  Cequier, E., et al. 2014. Anal Chim Acta. 845: 98-104. PMID: 25201278
  4. Kinetics of tris (1-chloro-2-propyl) phosphate (TCIPP) metabolism in human liver microsomes and serum.  |  Van den Eede, N., et al. 2016. Chemosphere. 144: 1299-305. PMID: 26473552
  5. Biotransformation of three phosphate flame retardants and plasticizers in primary human hepatocytes: untargeted metabolite screening and quantitative assessment.  |  Van den Eede, N., et al. 2016. J Appl Toxicol. 36: 1401-8. PMID: 26889657
  6. Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization.  |  Carignan, CC., et al. 2017. Environ Health Perspect. 125: 087018. PMID: 28858831
  7. Exposure to organophosphate flame retardant chemicals in the U.S. general population: Data from the 2013-2014 National Health and Nutrition Examination Survey.  |  Ospina, M., et al. 2018. Environ Int. 110: 32-41. PMID: 29102155
  8. Urinary metabolites of organophosphate esters in children in South China: Concentrations, profiles and estimated daily intake.  |  Chen, Y., et al. 2018. Environ Pollut. 235: 358-364. PMID: 29306213
  9. Simultaneous determination of 14 urinary biomarkers of exposure to organophosphate flame retardants and plasticizers by LC-MS/MS.  |  Bastiaensen, M., et al. 2018. Anal Bioanal Chem. 410: 7871-7880. PMID: 30291389
  10. Urinary metabolites of organophosphate flame retardants in China: Health risk from tris(2-chloroethyl) phosphate (TCEP) exposure.  |  Zhang, T., et al. 2018. Environ Int. 121: 1363-1371. PMID: 30420131
  11. Towards establishing indicative values for metabolites of organophosphate ester contaminants in human urine.  |  Bastiaensen, M., et al. 2019. Chemosphere. 236: 124348. PMID: 31326757
  12. Urinary metabolites of organophosphate esters and implications for exposure pathways in adolescents from Eastern China.  |  Ding, J., et al. 2019. Sci Total Environ. 695: 133894. PMID: 31425989
  13. Exposure to organophosphate flame esters during early pregnancy and risk of spontaneous abortion: A case-control study.  |  Zhao, Y., et al. 2021. Chemosphere. 268: 129375. PMID: 33360147
  14. Plasma concentrations of tris(1-chloro-2-propyl) phosphate and a metabolite bis(2-chloroisopropyl) 1-carboxyethyl phosphate in Sprague-Dawley rats and B6C3F1/N mice from a chronic study of tris(chloropropyl) phosphate via feed.  |  Collins, B., et al. 2022. Toxicol Rep. 9: 690-698. PMID: 35433273

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bis-(1-chloro-2-propyl)phosphate, 1 mg

sc-503804
1 mg
$583.00