Date published: 2025-11-15

1-800-457-3801

SCBT Portrait Logo
Seach Input

Bis(1,3-dichloro-2-propyl) Phosphate (CAS 72236-72-7)

0.0(0)
Write a reviewAsk a question

Alternate Names:
1,3-Dichloro-2-propanol Hydrogen Phosphate
Application:
Bis(1,3-dichloro-2-propyl) Phosphate is a metabolite of the flame retardant TDCPP
CAS Number:
72236-72-7
Molecular Weight:
319.93
Molecular Formula:
C6H11Cl4O4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Bis(1,3-dichloro-2-propyl) phosphate is a chemical compound primarily used for research into flame retardants and their environmental impact. In studies of material science, it is examined for its efficacy in reducing flammability of various substrates, including textiles and polymers. Environmental scientists study bis(1,3-dichloro-2-propyl) phosphate to understand its persistence and behavior in ecosystems, as well as its potential for bioaccumulation. It is also a subject of research in the field of analytical chemistry, where methods are developed to detect and quantify its presence in environmental samples, such as water, soil, and air. The compound′s role in the degradation of products and its release into the environment during and after use is an area of ongoing investigation.


Bis(1,3-dichloro-2-propyl) Phosphate (CAS 72236-72-7) References

  1. Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells.  |  Dishaw, LV., et al. 2011. Toxicol Appl Pharmacol. 256: 281-9. PMID: 21255595
  2. Analysis of the flame retardant metabolites bis(1,3-dichloro-2-propyl) phosphate (BDCPP) and diphenyl phosphate (DPP) in urine using liquid chromatography-tandem mass spectrometry.  |  Cooper, EM., et al. 2011. Anal Bioanal Chem. 401: 2123-32. PMID: 21830137
  3. Time-dependent effects of the flame retardant tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on mRNA expression, in vitro and in ovo, reveal optimal sampling times for rapidly metabolized compounds.  |  Farhat, A., et al. 2014. Environ Toxicol Chem. 33: 2842-9. PMID: 25242413
  4. Bioconcentration, metabolism and neurotoxicity of the organophorous flame retardant 1,3-dichloro 2-propyl phosphate (TDCPP) to zebrafish.  |  Wang, Q., et al. 2015. Aquat Toxicol. 158: 108-15. PMID: 25461749
  5. Developmental exposure to the organophosphorus flame retardant tris(1,3-dichloro-2-propyl) phosphate: estrogenic activity, endocrine disruption and reproductive effects on zebrafish.  |  Wang, Q., et al. 2015. Aquat Toxicol. 160: 163-71. PMID: 25637911
  6. Bioconcentration, metabolism and alterations of thyroid hormones of Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) in Zebrafish.  |  Xu, T., et al. 2015. Environ Toxicol Pharmacol. 40: 581-6. PMID: 26356387
  7. Parental exposure to tris(1,3-dichloro-2-propyl) phosphate results in thyroid endocrine disruption and inhibition of growth in zebrafish offspring.  |  Ren, X., et al. 2019. Aquat Toxicol. 209: 132-141. PMID: 30771614
  8. Review of emerging contaminant tris(1,3-dichloro-2-propyl)phosphate: Environmental occurrence, exposure, and risks to organisms and human health.  |  Wang, C., et al. 2020. Environ Int. 143: 105946. PMID: 32663715
  9. Precision Biotransformation of Emerging Pollutants by Human Cytochrome P450 Using Computational-Experimental Synergy: A Case Study of Tris(1,3-dichloro-2-propyl) Phosphate.  |  Chai, L., et al. 2021. Environ Sci Technol. 55: 14037-14050. PMID: 34663070
  10. Estimated tris(1,3-dichloro-2-propyl) phosphate exposure levels for US infants suggest potential health risks.  |  Hoffman, K., et al. 2017. Environ Sci Technol Lett. 4: 334-338. PMID: 34853794
  11. Tris(1,3-dichloro-2-propyl) phosphate is a metabolism-disrupting chemical in male mice.  |  Tenlep, SYN., et al. 2023. Toxicol Lett. 374: 31-39. PMID: 36493961
  12. Disposition of the flame retardant, tris(1,3-dichloro-2-propyl) phosphate, in the rat.  |  Lynn, RK., et al. 1981. Drug Metab Dispos. 9: 434-41. PMID: 6117442
  13. The metabolism and disposition of tris(1,3-dichloro-2-propyl) phosphate (Fyrol FR-2) in the rat.  |  Nomeir, AA., et al. 1981. Toxicol Appl Pharmacol. 57: 401-13. PMID: 7222047

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bis(1,3-dichloro-2-propyl) Phosphate, 50 mg

sc-391049
50 mg
$398.00