Date published: 2025-10-19

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Biotin-PEG2-Amine (CAS 138529-46-1)

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Alternate Names:
(+)-Biotin-(PEO)3-amine
Application:
Biotin-PEG2-Amine is Used in affinity purification of oligonucleotides
CAS Number:
138529-46-1
Molecular Weight:
374.50
Molecular Formula:
C16H30N4O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Biotin-PEG2-Amine is a water soluble biotin derivative that can be readily coupled to activated carboxylic acids. Amino-PEO tether imparts water solubility to this Biotin. The extended chain length (20.4 Å) increases avidin binding. Conjugation to substrates increases the aqueous solubility of the complex. It is used in affinity purification of oligonucleotides.


Biotin-PEG2-Amine (CAS 138529-46-1) References

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  2. Extending Single Molecule Imaging to Proteome Analysis by Quantitation of Fluorescent Labeling Homogeneity in Complex Protein Samples.  |  Leclerc, S., et al. 2018. Bioconjug Chem. 29: 2541-2549. PMID: 29975043
  3. Patterned plasmonic gradient for high-precision biosensing using a smartphone reader.  |  Bian, J., et al. 2019. Nanoscale. 11: 12471-12476. PMID: 31219124
  4. A visually distinguishable light interfering bioresponsive silica nanoparticle hydrogel sensor fabricated through the molecular imprinting technique.  |  Jinn, WS., et al. 2019. J Mater Chem B. 7: 7120-7128. PMID: 31602453
  5. Polymeric dipicolylamine based mass tags for mass cytometry.  |  Zhang, Y., et al. 2022. Chem Sci. 13: 3233-3243. PMID: 35414868
  6. Epigenetic regulation of the DNMT1/MT1G/KLF4/CA9 axis synergises the anticancer effects of sorafenib in hepatocellular carcinoma.  |  Wei, T., et al. 2022. Pharmacol Res. 180: 106244. PMID: 35550167
  7. Solid-Phase Total Synthesis of Sandramycin and Its Analogues.  |  Komatani, Y., et al. 2023. Org Lett. 25: 543-548. PMID: 36652724
  8. Payload-Binding Fab Fragments Increase the Therapeutic Index of MMAE Antibody-Drug Conjugates.  |  Bordeau, BM., et al. 2023. Mol Cancer Ther. 22: 459-470. PMID: 36723609
  9. New liquid chromatography columns for highlighting the interaction of ligand candidates with humic acid.  |  Guillaume, YC. and André, C. 2023. J Sep Sci. e2300203. PMID: 37254734
  10. Controlling biotinylation of microgels and modeling streptavidin uptake  |  , et al. (2011). Colloid and Polymer Science. volume 289,: pages 659–666.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Biotin-PEG2-Amine, 5 mg

sc-496447A
5 mg
$126.00

Biotin-PEG2-Amine, 100 mg

sc-496447
100 mg
$365.00