Date published: 2025-10-16

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(+)-Biotin hydrazide (CAS 66640-86-6)

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Alternate Names:
Biotin hydrazide; Biotin-NHNH2; D-Biotin Hydrazide
Application:
(+)-Biotin hydrazide is a functionalized derivative that allows biotinylation of glycoproteins and glycolipids
CAS Number:
66640-86-6
Molecular Weight:
258.34
Molecular Formula:
C10H18N4O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(+)-Biotin hydrazide is a compound that functions as a specific labeling reagent in various biochemical and biotechnological applications. It acts by forming a stable covalent bond with aldehydes or ketones, allowing for the selective labeling of these functional groups in proteins, nucleic acids, and other biomolecules. (+)-Biotin Hydrazide′s mechanism of action involves the formation of a hydrazone bond with the carbonyl group of the target molecule, enabling the attachment of biotin to the labeled molecule. This facilitates the subsequent detection, purification, or immobilization of the labeled biomolecules using avidin or streptavidin-based detection systems. In this way, (+)-Biotin hydrazide plays a role in enabling the specific and sensitive detection and analysis of biomolecules in various experimental applications.


(+)-Biotin hydrazide (CAS 66640-86-6) References

  1. The MYO1B and MYO5B motor proteins and the SNX27 sorting nexin regulate membrane mucin MUC17 trafficking in enterocytes.  |  Jäverfelt, S., et al. 2023. bioRxiv.. PMID: 36945389
  2. Synthesis of N-[6-(ethylendioxy) hexyl] biotinamide: A biotinyl aldehyde precursor for labeling hydrazine-modified biomolecules  |  Musso, G. F., Scarlato, G. R., & Ghosh, S. S. 1992. Bioconjugate chemistry. 3(1): 88-90.
  3. Synthesis of surface-functionalized, probe-containing, polymerized vesicles derived from ammonium bromide surfactants  |  Guo, C. Y., Shankar, R. R., Cai, S. H., Wu, J. Q., Abe, S., Thomas, R. N.,.. & Kiang, H. 1992. Langmuir. 8(3): 815-823.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(+)-Biotin hydrazide, 100 mg

sc-239344
100 mg
$84.00

(+)-Biotin hydrazide, 1 g

sc-239344A
1 g
$437.00

What is the solubility of sc-239344?

Asked by: SCchem16
Thank you for your question. This chemical, (+)-Biotin hydrazide: sc-239344, is soluble in DMSO at ≤20 mg/mL.
Answered by: Chemical Support 2
Date published: 2017-02-01
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Rated 5 out of 5 by from We have no complaints for this reagentWe have no complaints for this reagent.
Date published: 2015-03-24
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(+)-Biotin hydrazide is rated 5.0 out of 5 by 1.
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