Date published: 2026-4-25

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Biotin C2 maleimide

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Molecular Weight:
366.44
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Biotin C2 maleimide is a chemical compound that functions as a reactive probe in biochemical and cellular studies. Its primary mode of action involves the covalent modification of sulfhydryl groups on proteins, allowing for the specific labeling and detection of these proteins in complex biological samples. Biotin C2 maleimide is utilized to study protein-protein interactions, protein localization, and protein function within cells. Biotin C2 maleimide achieves this by forming stable thioether bonds with cysteine residues on target proteins, enabling their visualization and analysis using streptavidin-based detection methods. Through this mechanism, Biotin C2 maleimide serves as useful for investigating the dynamics and behavior of proteins in various biological systems, contributing to the advancement of scientific knowledge in the field of molecular biology and biochemistry.


Biotin C2 maleimide References

  1. Distinct conformational spectrum of homologous multidrug ABC transporters.  |  Moeller, A., et al. 2015. Structure. 23: 450-460. PMID: 25661651
  2. A Photo-Crosslinking Approach to Identify Class II SUMO-1 Binders.  |  Brüninghoff, K., et al. 2022. Front Chem. 10: 900989. PMID: 35707458
  3. Design and Evolution of Enhanced Peptide-Peptide Ligation for Modular Transglutaminase Assembly.  |  Keeble, AH., et al. 2023. Bioconjug Chem.. PMID: 37289810

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Biotin C2 maleimide, 25 mg

sc-499377
25 mg
$416.00