Biocytin (CAS 576-19-2)
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Biocytin is a versatile marker used for neuroanatomical studies and biotinidase assays. Biocytin is water soluble and can be easily detected by avidin and streptavidin conjugates. Also known as vitamin B7 or biotin, is a biologically active form of this essential nutrient. It serves as a cofactor for various carboxylases responsible for metabolizing fatty acids and amino acids. While it occurs naturally in food sources, it can also be synthesized in laboratory applications. Biocytin exhibits a diverse array of biological activities, including antioxidant, anti-inflammatory, and antineoplastic properties. Furthermore, extensive research has been conducted on biocytin to explore its potential in modulating gene expression and cell signaling pathways, highlighting its significance in the field of molecular biology.
Biocytin (CAS 576-19-2) References
- Interference of biocytin with opioid-evoked hyperpolarization and membrane properties of rat spinal substantia gelatinosa neurons. | Eckert, WA., et al. 2001. Neurosci Lett. 297: 117-20. PMID: 11121884
- Biocytin and biotin uptake into NB2a neuroblastoma and C6 astrocytoma cells. | Baur, B., et al. 2002. Brain Res. 925: 111-21. PMID: 11792359
- Use of biocytin as neuroanatomic tracer in harvested human pancreas: a confocal laser scanning microscopy analysis. | Spiga, S., et al. 2002. Pancreas. 24: 329-35. PMID: 11961484
- Biocytin injections produce selective neuronal labeling in the rat CNS. | McDonald, AJ., et al. 1992. Neuroreport. 3: 337-40. PMID: 1515592
- Biocytin filling of adult gonadotropin-releasing hormone neurons in situ reveals extensive, spiny, dendritic processes. | Campbell, RE., et al. 2005. Endocrinology. 146: 1163-9. PMID: 15564319
- Biocytin wide-field bipolar cells in rabbit retina selectively contact blue cones. | MacNeil, MA. and Gaul, PA. 2008. J Comp Neurol. 506: 6-15. PMID: 17990268
- Improved neuronal tract tracing with stable biocytin-derived neuroimaging agents. | Mishra, A., et al. 2010. ACS Chem Neurosci. 1: 129-38. PMID: 22778821
- Biocytin-derived MRI contrast agent for longitudinal brain connectivity studies. | Mishra, A., et al. 2011. ACS Chem Neurosci. 2: 578-87. PMID: 22860157
- Biocytin: a versatile anterograde neuroanatomical tract-tracing alternative. | King, MA., et al. 1989. Brain Res. 497: 361-7. PMID: 2479450
- Biocytin staining of glia and neurons in brain slices. | Kang, J. 2014. Cold Spring Harb Protoc. 2014: 948-50. PMID: 25183822
- Double-staining of horizontal and amacrine cells by intracellular injection with lucifer yellow and biocytin in carp retina. | Teranishi, T. and Negishi, K. 1994. Neuroscience. 59: 217-26. PMID: 7514770
- Biotinylation of biotinidase following incubation with biocytin. | Hymes, J., et al. 1995. Clin Chim Acta. 233: 39-45. PMID: 7758201
- Fluorophore-linked assays for high-performance liquid chromatography postcolumn reaction detection of biotin and biocytin. | Hentz, NG. and Bachas, LG. 1997. Methods Enzymol. 279: 275-86. PMID: 9211279
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Biocytin, 10 mg | sc-203845 | 10 mg | $42.00 | |||
Biocytin, 50 mg | sc-203845A | 50 mg | $122.00 |