Molecular structure of Binucleine 2, CAS Number: 220088-42-6
Binucleine 2 (CAS 220088-42-6)
Alternate Names:
N′-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide
Application:
Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway
CAS Number:
220088-42-6
Purity:
≥97%
Molecular Weight:
291.71
Molecular Formula:
C13H11ClFN5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Binucleine 2 is a cell-permeable pyrazolo compound that inhibits cytokinesis function of the Aurora B kinase pathway. Inhibits Histone H3 phosphorylation on Ser10 in mitotic Drosophila Kc167 cells at 20 µM, while inactive in mammalian systems. Binucleine 2 does neither function as a general kinase inhibitor nor inhibit Cdk-dependent entry into mitosis.
Binucleine 2 (CAS 220088-42-6) References
Eggert, U.S., et al. 2004. PLoS Biol. 2, 2135.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Binucleine 2, 5 mg | sc-202500 | 5 mg | $162.00 |