Molecular structure of Biliverdine, CAS Number: 114-25-0
Biliverdine (CAS 114-25-0)
Alternate Names:
3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetrametyl-1,19-dioxo-21H-biline-8,12-dipropanoic Acid
Application:
Biliverdine is a precursor of Bilirubin
CAS Number:
114-25-0
Molecular Weight:
582.65
Molecular Formula:
C33H34N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Biliverdine is a precursor of Bilirubin that is formed in the body from hemoglobin. Biliverdin serves as a precursor and porphyrin bile pigment in the biosynthesis pathway of bilirubin. It is generated through the oxidative breakdown of heme by heme oxygenase-1 (HO-1), and subsequently converted to bilirubin by biliverdin reductase. At concentrations exceeding 0.5 µM, biliverdin exhibits antioxidant properties as demonstrated in oxygen radical absorbance capacity (ORAC) and Trolox equivalent absorbance capacity (TEAC) assays.
Biliverdine (CAS 114-25-0) References
- Carbon monoxide is the heme oxygenase product with a pyretic action: evidence for a cGMP signaling pathway. | Steiner, AA. and Branco, LG. 2001. Am J Physiol Regul Integr Comp Physiol. 280: R448-57. PMID: 11208574
- Effects of carbon monoxide and heme oxygenase inhibitors in cerebral vessels of rats and mice. | Andresen, JJ., et al. 2006. Am J Physiol Heart Circ Physiol. 291: H223-30. PMID: 16489113
- Central heme oxygenase-carbon monoxide pathway participates in the lipopolysaccharide-induced tolerance in rats. | Raffaini, MS., et al. 2006. Brain Res. 1111: 83-9. PMID: 16901472
- 2',4',6'-tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways. | Lee, SH., et al. 2007. Biochem Pharmacol. 74: 870-80. PMID: 17678632
- Protective effects of heme oxygenase-1 against MPP(+)-induced cytotoxicity in PC-12 cells. | Bae, JW., et al. 2010. Neurol Sci. 31: 307-13. PMID: 20127499
- [Influence of corpora allata on the pigmentation of carausius morosus Br.]. | Gesa, B. 1973. Wilhelm Roux Arch Entwickl Mech Org. 173: 249-262. PMID: 28304875
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Biliverdine, 10 mg | sc-207357 | 10 mg | $350.00 |