Bifenazate (CAS 149877-41-8)
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Bifenazate, a carbazate acaricide, demonstrates exceptional efficacy in mite control at a concentration of 25 ppm, providing a 100% control rate. This compound acts as a positive allosteric modulator of GABA receptors, specifically the resistance to dieldrin (Rdl) subunit homolog TuGABAR found in T. urticae (spider mites). By employing a concentration of 30 µM, bifenazate effectively alters the GABA-induced response from an EC50 value of 24.8 to 4.83 µM. The utilization of bifenazate formulations has proven instrumental in mite control and pesticide detection. Primarily utilized for the management of phytophagous mites infesting agricultural and ornamental crops, bifenazate serves as a selective carbazate acaricide. This compound is a carboxylic ester resulting from the condensation of 2-(4-methoxy[1,1′-biphenyl]-3-yl)hydrazinecarboxylic acid with 2-propanol. Its role as an acaricide stems from its derivation from a carbazic acid and a hydride of a biphenyl.
Bifenazate (CAS 149877-41-8) References
- Complete maternal inheritance of bifenazate resistance in Tetranychus urticae Koch (Acari: Tetranychidae) and its implications in mode of action considerations. | Van Leeuwen, T., et al. 2006. Insect Biochem Mol Biol. 36: 869-77. PMID: 17046600
- Toxicity of bifenazate and its principal active metabolite, diazene, to Tetranychus urticae and Panonychus citri and their relative toxicity to the predaceous mites, Phytoseiulus persimilis and Neoseiulus californicus. | Ochiai, N., et al. 2007. Exp Appl Acarol. 43: 181-97. PMID: 17972019
- Dissipation kinetics of bifenazate in tea under tropical conditions. | Satheshkumar, A., et al. 2014. Food Chem. 145: 1092-6. PMID: 24128589
- Unravelling the reactivity of bifenazate in water and on vegetables: Kinetics and byproducts. | Hamdache, S., et al. 2018. Sci Total Environ. 636: 107-114. PMID: 29704707
- Peer review of the pesticide risk assessment of the active substance bifenazate. | ,. 2017. EFSA J. 15: e04693. PMID: 32625279
- Modification of the existing maximum residue level for bifenazate in soya bean. | , ., et al. 2017. EFSA J. 15: e04983. PMID: 32625647
- Bifenazate exposure induces cardiotoxicity in zebrafish embryos. | Ma, J., et al. 2021. Environ Pollut. 274: 116539. PMID: 33549839
- Residues and Safety Evaluation of Etoxazole, Bifenazate and Its Metabolite Bifenazate-diazene in Citrus Under Open-Field Conditions. | Hou, H., et al. 2021. Bull Environ Contam Toxicol. 107: 281-288. PMID: 34264365
- Updated peer review of the pesticide risk assessment of the active substance bifenazate. | , ., et al. 2021. EFSA J. 19: e06818. PMID: 34484448
- Sublethal effects of bifenazate on biological traits and enzymatic properties in the Panonychus citri (Acari: Tetranychidae). | Wang, H., et al. 2021. Sci Rep. 11: 20934. PMID: 34686836
- Dissipation, Residue, and Dietary Risk Assessment of Bifenthrin, Bifenazate, and Its Metabolite Bifenazate-Diazene in Apples Based on Deterministic and Probabilistic Methods. | Zhao, P., et al. 2021. J Agric Food Chem. 69: 14302-14310. PMID: 34806379
- Residue distribution and risk assessment of bifenazate and its metabolite in garlic plant. | Bian, Y., et al. 2022. Food Chem. 379: 132013. PMID: 35063852
- Transcriptome Analysis to Identify Responsive Genes under Sublethal Concentration of Bifenazate in the Diamondback Moth, Plutella xylostella (Linnaeus, 1758) (Lepidoptera: Plutellidae). | Hou, Q., et al. 2022. Int J Mol Sci. 23: PMID: 36361960
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bifenazate, 1 g | sc-503557 | 1 g | $311.00 |