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Bifemelane hydrochloride (CAS 62232-46-6)

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Alternate Names:
2-(4-Methylaminobutoxy)diphenylmethane hydrochloride
CAS Number:
62232-46-6
Purity:
≥99%
Molecular Weight:
305.84
Molecular Formula:
C18H23NO•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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MAO-A and MAO-B inhibitor. Increases locomotor activity in MPTP-treated marmosets and reverses catalepsy induced by tetrabenazine in mice.


Bifemelane hydrochloride (CAS 62232-46-6) References

  1. Bifemelane hydrochloride protects against cytotoxicity of hydrogen peroxide on cultured rat neuroblastoma cell line.  |  Miyazaki, I., et al. 1999. Neurochem Res. 24: 857-60. PMID: 10403625
  2. Comparison of the effects of bifemelane hydrochloride, idebenone and indeloxazine hydrochloride on ischemia-induced changes in brain monoamines and their metabolites in gerbils.  |  Haba, K., et al. 1992. J Neural Transm Gen Sect. 88: 187-98. PMID: 1384558
  3. Bifemelane hydrochloride reduces plasma beta-endorphin-like immunoreactivity levels in rats.  |  Mitsuma, T., et al. 1990. Exp Clin Endocrinol. 95: 301-5. PMID: 2245819
  4. Effects of bifemelane hydrochloride on cortical neuronal activity in cats.  |  Egawa, M., et al. 1987. Neuropharmacology. 26: 379-84. PMID: 2884591
  5. Comparison of the effects of bifemelane hydrochloride and indeloxazine hydrochloride on scopolamine hydrobromide-induced impairment in radial maze performance.  |  Ogawa, N., et al. 1988. Clin Ther. 10: 704-11. PMID: 3219685
  6. 4-(O-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(O-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase.  |  Naoi, M., et al. 1988. J Neurochem. 50: 243-7. PMID: 3335842
  7. Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCI-2016), a new psychotropic drug with antidepressant activity.  |  Tobe, A., et al. 1981. Arzneimittelforschung. 31: 1278-85. PMID: 7197535
  8. Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset.  |  Nomoto, M., et al. 1994. Neurosci Lett. 178: 95-8. PMID: 7816348
  9. Effects of bifemelane hydrochloride on cerebral circulation and metabolism in patients with aphasia.  |  Kabasawa, H., et al. 1994. Clin Ther. 16: 471-82. PMID: 7923314
  10. Effects of bifemelane hydrochloride on atherosclerosis in aged rats fed low-calcium diets.  |  Yasui, M., et al. 1996. J Int Med Res. 24: 454-65. PMID: 8959529

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bifemelane hydrochloride, 10 mg

sc-203529
10 mg
$280.00

Bifemelane hydrochloride, 50 mg

sc-203529A
50 mg
$800.00